Medicilon offers integrated pharmaceutical services designed to
further your drug discovery and development efforts.
Medicilon was founded in 2003 to provide custom drug discovery services to the
pharmaceutical and biotech community. The company is located in the Zhangjiang Hi-
Tech Park in Shanghai, China and occupies 85,000 square feet of R&D facilities with
300 scientists. Medicilon also maintains lab space in the Chicago Technology Park in
Chicago, IL. The company is managed by a team with extensive experience in drug
discovery and development in US pharmaceutical and biotech companies.
Medicilon will combine the following elements of a discovery and development program as
necessary in order to meet your needs. While our specialty and focus is on integrated
programs, we will be happy to offer all services separately, based on your needs.
Components included in drug discovery and development programs:
 | Custom Chemical Synthesis |
- High throughput parallel synthesis of screening compounds and focused combinatorial
libraries - Combinatorial building blocks
- Intermediates
- Reference compounds
- Drug candidates
| Pharmacokinetics |
- Absorption, distribution, metabolism and elimination studies
- Protocol design
- Formulation development
- In-life study
- Sample and data analysis
- Report preparation
| Metabolism |
| Bioanalytical |
| Structural Biology Service |
- Gene-to-protein and Gene-to-structure
- Crystallization/co-crystallization or soaking
- Synchrotron data collection at Argonne, Chicago
- Structural determination
| Other Biology services |
- Cloning and plasmid construction, mutagenesis
- Culture, transient and stable transfection and subcloning of mammalian cell lines
- Scale up expression with 10-36 L bioreactors; e. coli, insect cell and mammalian cells
- Protein purification with multi-step columns, with western, SDS, MASS Spec QC
- Custom cell line supply and maintenance
- Activity validation and Assay development, etc
| Pharmacology |
| Animal Models | |
Medicilon
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