Medicilon offers integrated pharmaceutical services designed to further your drug discovery and development efforts.
Medicilon was founded in 2003 to provide custom drug discovery services to the pharmaceutical and biotech community. The company is located in the Zhangjiang Hi- Tech Park in Shanghai, China and occupies 85,000 square feet of R&D facilities with 300 scientists. Medicilon also maintains lab space in the Chicago Technology Park in Chicago, IL. The company is managed by a team with extensive experience in drug discovery and development in US pharmaceutical and biotech companies.
Medicilon will combine the following elements of a discovery and development program as necessary in order to meet your needs. While our specialty and focus is on integrated programs, we will be happy to offer all services separately, based on your needs.
Components included in drug discovery and development programs:
Custom Chemical Synthesis
High throughput parallel synthesis of screening compounds and focused combinatorial libraries
Combinatorial building blocks
Intermediates
Reference compounds
Drug candidates
Pharmacokinetics
Absorption, distribution, metabolism and elimination studies
Protocol design
Formulation development
In-life study
Sample and data analysis
Report preparation
Metabolism
Bioanalytical
Structural Biology Service
Gene-to-protein and Gene-to-structure
Crystallization/co-crystallization or soaking
Synchrotron data collection at Argonne, Chicago
Structural determination
Other Biology services
Cloning and plasmid construction, mutagenesis
Culture, transient and stable transfection and subcloning of mammalian cell lines
Scale up expression with 10-36 L bioreactors; e. coli, insect cell and mammalian cells
Protein purification with multi-step columns, with western, SDS, MASS Spec QC