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The SAPA-CT Annual Conference will take place in New Haven, CT on Oct 19, 2019.  Sino-American Pharmaceutical Professionals Association (SAPA) was founded in 1993 and grew rapidly and has become one of the most active and well-recognized Chinese-heritage enduring professional organizations in the United States. SAPA is an independent, nonprofit and professional organization with over 4,000Read more

Recently, ImmuneOnco Biopharma, a partner of Shanghai Medicilon Inc., announced that its newly developed immune checkpoint inhibitor has been approved by the National Medical Products Administration (NMPA), which marks the beginning of a new phase of research on the first CD47 fusion protein drug in China. It is reported that ImmuneOnco Biopharma submitted the INDRead more

Every animal model of disease comes with its own unique set of drawbacks. Yet, scientists continually push to improve the quality of animal models to recapitulate the physiological and molecular signatures of disease states. For decades, researchers have turned to mice whose immune systems have been “humanized” to respond in a manner similar to humans.Read more

Scientists at the Van Andel Research Institute have developed a novel biochemical platform to research a family of enzymes that are promising targets for cancer treatment. The study (“A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity”), published in Science Advances, describes a new method that provides a high-resolution view of howRead more

Don’t be alarmed, but a bacterium that could turn deadly is on your skin right now. This bacterium, Staphylococcus epidermis, is usually harmless, but it may harbor genes that could help it exploit any opportunity to grow in your bloodstream. Once there, it could shrug off your immune response, resist the antibiotics you receive, andRead more

The largest study of CRISPR action to date has developed a method to predict the exact mutations CRISPR-Cas9 gene editing can introduce to a cell. Researchers at the Wellcome Sanger Institute edited 40,000 different pieces of DNA and analysed a thousand million resulting DNA sequences to reveal the effects of the gene editing and developRead more

Researchers at the University of California, San Francisco (UCSF) report that they have discovered why some lung cancers become drug-resistant after initially responding to targeted therapies. In the process, they say they devised a new two-pronged approach that yields an effective treatment for these cancers in the laboratory and holds promise for the future ofRead more

An international team of scientists has identified a protein that boosts the energy-burning activity of brown fat in mice, and which could feasibly lead to the development of new therapeutic approaches for treating obesity in humans. The research, headed by a team at the University of Cambridge, U.K., showed that the protein, BMP8b, effectively superchargesRead more

Imagine a DNA database populated with data from every individual in society and made available to law enforcement. Such a database sounds ominous, especially if you’ve watched Black Mirror or similarly dystopian-themed programs. But such a DNA database could also be reassuring, suggests a team of scientific and policy experts at Vanderbilt University. According toRead more

Understanding the genetic makeup of complex chronic diseases is a significant step toward developing advanced diagnostics and better treatment options. In that vein, an international team of investigators led by scientists at the University of Manchester put together an extensive genome-wide association study (GWAS) to identify the genetic factors that predispose people to chronic kidneyRead more