Blog

The tiny Teste fly has been a scourge for centuries in many parts of Africa, spreading the debilitating and even deadly disease called African sleeping sickness. Now, investigators from Clemson University have released new findings focusing on the biological cues that signal the parasite which causes the disease – Trypanosoma brucei – to change lifeRead more

Epigenetic regulators that modify factors involved in switching genes on and off represent attractive anticancer targets, but whether this strategy will work in vivo hasn’t yet been proven. Studies in mice by researchers headed by a Boston Children’s Hospital team now suggest that blocking one epigenetic regulator – a histone methyltransferase known as G9a –Read more

The battle between medicine and harmful bacteria has traditionally centered on the hunt for new antimicrobial drugs, but the pathogens almost inevitably develop resistance to every type of antibiotic developed. A team at the University of Washington (UW), Seattle, has now developed a new strategy that thwarts this ability to develop antimicrobial drug resistance (AMR)Read more

Scientists from Germany and Finland report that brown fat interacts with the gut hormone secretin in mice to relay nutritional signals about fullness to the brain during a meal. The study (“Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation”), published in Cell, reinforces our understanding of a long-suspected role of brown adipose tissue, a typeRead more

Scientists at Virginia Tech, led by Jennifer Munson, Ph.D., an assistant professor in the department of biomedical engineering and mechanics in the College of Engineering, say they may have found a solution to stopping the spread of glioblastoma.   In an article (“Convective forces increase CXCR4-dependent glioblastoma cell invasion in GL261 murine model”) published in ScientificRead more

Old age is the greatest risk factor for many diseases, including Alzheimer’s disease (AD) and cancer. Geroprotectors are a recently identified class of anti-aging compounds.   Scientists at the Salk Institute have identified a new subclass of anti-aging geroprotector compounds that can slow aging in mice and could represent promising drug candidates for Alzheimer’s diseaseRead more

Improving how chemotherapy is delivered to cancer cells is a major concern for researchers and drug manufacturers. One of the big issues with chemotherapy is that most treatment approaches focus on the tumor itself without paying significant attention to the microenvironment surrounding the tumor. Now, investigators at Purdue University have developed new technology aimed atRead more

  Thanksgiving is the time to say thanks to our valued partners, colleagues and friends. In this time of gratitude, we give thanks for you.  We value your patronage and appreciate your confidence in us. Counting you among our clients is something for which we are especially grateful. Medicilon wish you a very happy, warmRead more

Outbreaks of norovirus in health care settings and outbreaks caused by a particular genotype of the virus are more likely to make people seriously ill, according to a new study (“The Norovirus Epidemiologic Triad: Predictors of Severe Outcomes in US Norovirus Outbreaks, 2009–2016”) by the Centers for Disease Control and Prevention (CDC) in The Journal of Infectious Diseases.Read more

Traditional herbal medicines used for centuries often have tangible physiologic and therapeutic value. Yet, for these remedies to be successful for the masses the underlying cellular and molecular properties need to be carefully teased out and assessed for safety and effectiveness. In that vein, investigators in the department of physiology & biophysics at the UniversityRead more