Medicilon can help you develop assays to screen your compounds or against focused libraries synthesized by our chemists. We provide both enzyme and cell based assays. We have successfully constructed several GPCR stable cell lines and complete tens of kinase profiling and IC50 determination which can effectively drive your drug discovery process. Assay development work to support hit identification, hit to lead and lead optimization process.

GPCR
·GPCR stable cell line construction
·GPCR based screening

Kinase
·Kinetics
·Kinas’ based screening
·IC50 determination
·Kinase profiling

Assay development and screening
·Phosphatase assays
·Protease assays
·Kinetics assays
·Cell viability assays
·Binding assays
·Nucleus receptor assays
·Cell imaging assays

Assay technology platforms
·Fluorescence
·Luminescence
·Fluorescence resonance energy transfer (FRET)
·Fluorescence polarization (FP)
·Absorbance
·Radioactivity