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Long ago, a “dead gene” buried in the genomes of groundhog-sized animals gained the ability to jerk back to life. The gene, called leukemia inhibitory factor 6 (LIF6), stirs when it is alerted to DNA damage. Then it expresses a protein that staggers around until it latches onto mitochondria and gnaws on them, spilling theirRead more

In the U.S. alone, there are over one million individuals living with HIV and 1 in 7 of them don’t know they are infected. As antimicrobial resistance is a growing global public health threat, researchers are actively taking steps to minimize the emergence and spread of HIV drug resistance – as well as treating currentRead more

Scientists in the U.S. and Korea have developed a statistical method for estimating the broad numbers of DNA variations that impact on different physical traits, such as height or childhood IQ, and on a wide range of diseases, from diabetes to bipolar disorder.   Their findings, derived from analyses of existing genome-wide association studies (GWAS),Read more

The immune system is not typically taken into consideration by neuroscientists when discussing sexual behavior in the developing brain. Yet now, a new study from investigators at The Ohio State University (OSU) may have many scientists rethinking behavioral development, as the researchers found a surprising new explanation of how young brains are shaped for sexualRead more

The delivery of therapies specifically to cancer cells has always been hindered by limitations of the delivery molecules – all too often off-target effects can be detrimental to a patient’s overall health. Moreover, while chemotherapies have been highly useful as targeted treatments for cancer, unwanted side effects still plague therapeutic outcomes. However now, researchers atRead more