Our Pharmacology department functions in accordance with the needs of our customers for a variety of effective animal models used to detect drug effectiveness. We offer non-human primates, dogs, mice and rats, rabbits, guinea pigs and others in our services.
Disease | Model | Species |
Analgesia | Hot-Plate | Mouse/Rat |
Tail flick | Mouse/Rat | |
Radiant heat pain | Mouse/Rat | |
Pressing pain | Mouse/Rat | |
Formalin test (phase I & phase II) | Mouse/Rat | |
Complete freund’s adjuvant, CFA | Rat | |
Acetic acid induced writhing | Mouse | |
LPS-induced thermal hyperalgesia | Guinea pig | |
Selective spinal nerve ligation (SNL) | Rat | |
Sciatic nerve injury model(SNI) | Rat | |
STZ-induced diabetic neuropathy | Rat | |
Hippocampal cell apoptosis and behavioral performance after hypoxia-ischemia brain injury | Mouse | |
Sedative-hypnotic and antianxiety | Potentiated pentobarbital-induced sleep | Mouse |
Open fild test | Mouse/Rat | |
Elevated plus maze test | ||
Shuttle box test | Rat | |
Anticonvulsant Tests
|
Toxicity enhancement experiment with yohinbine | Mouse |
Pentylenetetrazol convulsions | Mouse | |
Picrotoxin convulsions | mouse | |
Disease | Model | Species |
Antidepressant
Tests |
Forced swimming test | Mouse/Rat |
Tail suspension test | Mouse | |
5-HTP-induced head twitches potentiation (5-HT) | Mouse | |
Reserpine-induced ptosis | Mouse | |
Yohimbine-induced lethality | Mouse | |
High-dose apomorphine antagonism | ||
Chronic unpredictable mild stimulations (CUMS) | Mouse | |
MAO-A、MAO-B activity test | Rat | |
Anti-Parkinson Tests | Oxotremorine-induced Tremors/Salivation | Mouse |
Reserpine Antagonism | Mouse | |
MPTP model | Rat | |
Antidementia Tests | Morris water maze | Mouse/Rat |
In light –dark box test | Mouse | |
memory retrieval impairment | Mouse | |
memory consolidating impairment | Mouse | |
Activity of acetylcholinesterase test | Mouse | |
D-galactose model | Mouse | |
APP/PS1 | Mouse | |
Antipsychotic Tests | MK801 induced chizophrenia with positive/negative symptom | Mouse |
Ketamine induced chizophrenia with positive symptom | Mouse | |
catalepsy | Rat |