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Neurological Disorders Models

Home Service Neurological Disorders Models

Our Pharmacology department functions in accordance with the needs of our customers for a variety of effective animal models used to detect drug effectiveness. We offer non-human primates, dogs, mice and rats, rabbits, guinea pigs and others in our services.

Disease Model Species
Analgesia Hot-Plate Mouse/Rat
Tail flick Mouse/Rat
Radiant heat pain Mouse/Rat
Pressing pain Mouse/Rat
Formalin test (phase I & phase II) Mouse/Rat
Complete freund’s adjuvant, CFA Rat
Acetic acid induced writhing Mouse
LPS-induced thermal hyperalgesia Guinea pig
Selective spinal nerve ligation (SNL) Rat
Sciatic nerve injury model(SNI) Rat
STZ-induced diabetic neuropathy Rat
Hippocampal cell apoptosis and behavioral performance after hypoxia-ischemia brain injury Mouse
Sedative-hypnotic and antianxiety Potentiated pentobarbital-induced sleep Mouse
Open fild  test  Mouse/Rat
Elevated plus maze test
Shuttle box test Rat
Anticonvulsant Tests

 

Toxicity enhancement experiment with yohinbine Mouse
Pentylenetetrazol convulsions Mouse
Picrotoxin convulsions mouse
 Disease Model  Species
Antidepressant

Tests

Forced swimming test Mouse/Rat
Tail suspension test Mouse
5-HTP-induced head twitches potentiation (5-HT) Mouse
Reserpine-induced ptosis Mouse
Yohimbine-induced lethality Mouse
High-dose apomorphine antagonism
Chronic unpredictable mild stimulations (CUMS) Mouse
MAO-A、MAO-B activity test  Rat
Anti-Parkinson Tests Oxotremorine-induced Tremors/Salivation Mouse
Reserpine Antagonism Mouse
MPTP model Rat
Antidementia Tests Morris water maze Mouse/Rat
In light –dark box test  Mouse
memory retrieval impairment  Mouse
memory consolidating impairment  Mouse
Activity of acetylcholinesterase test  Mouse
D-galactose model  Mouse
APP/PS1  Mouse
Antipsychotic Tests MK801 induced chizophrenia with positive/negative symptom  Mouse
Ketamine induced chizophrenia with positive symptom  Mouse
catalepsy  Rat
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  • Medicilon Overview
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  • Corporate Culture
  • Honor

Services

  • Chemistry
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  • Bioanalytical
  • Drug Safety Evaluation
  • Formulation Development
  • Pharmacology
  • Pharmacokinetic
  • Integrated Projects

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Shanghai Medicilon Inc.

Address: No. 585, Chuanda Road, Pudong, Shanghai, 201200, China
Email: Marketing@medicilon.com
Website: www.medicilon.com

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  • Home
  • About
    • Medicilon Overview
    • Executive Team
    • CEO Message
    • Corporate Culture
    • Company History
    • Honor
  • Services
    • Integrated Projects
      • Antibody-Drug-Antibody (ADC)
      • Preclinical Research Services
      • IND Filing
      • Bio Drug Development
      • Chemical Drug Development
      • Chemical Compound Druggability Assessment
      • Molecular Imaging & Radiochemistry
      • OINDP Development
      • Preclinical Ophthalmic Research Platform
    • Pharmacology Services
      • Cancer Xenograft Models
      • Orthotopic Models
      • Syngeneic Mouse Models
      • Transgenic Mouse Model
      • Humanized Mouse Model (hPBMCEngrafted)
      • PDX Model
      • Digestive System Models
      • Neurological Disorders Models
      • Metabolic Disease Models
      • Inflammation & Immunological Disease Models
      • Other Disease Models
    • Chemistry Services
      • Medicinal Chemistry Services
      • Synthetic Chemistry
      • Process Development Services
      • Analytical Chemistry
    • Drug Formulation
      • Pre Formulation Development
      • Analytical Development
      • Formulation Development Services
      • Generics Consistency Evaluation
      • Research on Quality Control
      • Clinical Trial Material
      • OINDP Development
    • Biology Services
      • Discovery Biology Services
      • Recombinant Protein Services
      • Computational Biology & Molecular Modeling
      • Crystallization & Structural Determination
      • Kinase Services
      • SeMet Media Sales
    • Bioanalytical Services
      • Large Molecule Bioanalysis
      • Small Molecule Bioanalysis
    • Pharmacokinetic Services
      • In Vivo Assays
      • In Vitro Assays
    • Drug Safety Evaluation
      • Inhalation Toxicity Assessment
  • Customer
    • Customer Reviews
    • New Models of Collaboration
    • Intellectual Property Protection
    • Download Center
  • Careers
  • News
    • Medicilon Events
    • Media Coverage
    • Featured Stories
  • Contact
Medicilon Inc