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Home Search results for "neurological disorders"

Alzheimer’s Disease Linked to Loss of Epigenetic Protection

By medicilon | Featured Stories | Comments are Closed | 17 May, 2018 |

An international team of researchers has linked a gene known as peptidase M20-domain-containing protein 1 (PM20D1) with Alzheimer’s disease (AD) in humans. An analysis of genetic and epigenetic study data, combined with data from human tissue samples and subsequent experiments in mouse models, indicated that increased levels of PM20D1 in the brain have a protectiveRead more

Optogenetic Studies Get Major Boost from Advanced Novel Microscope

By medicilon | Featured Stories | Comments are Closed | 1 December, 2017 |

Scientists from Harvard report the development of a new microscope that greatly improves researchers’ ability to study how neurological disorders such as epilepsy and Alzheimer’s disease affect neuronal communication. The microscope is optimized to perform studies using optogenetic techniques that use light to control and image neurons genetically modified with light-sensitive proteins. “Our new microscopeRead more

Gene Silencing Drug Holds Potential to Treat Fatal Neurological Conditions

By medicilon | Featured Stories | 0 comment | 17 April, 2017 |

    Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease that is characterized by motor neuron loss and that leads to paralysis and death 2–5 years after disease onset.  Nearly all patients with ALS have aggregates of the RNA-binding protein TDP-43 in their brains and spinal cords, and rare mutations in the gene encoding TDP-43Read more

Different Neurological Disorders Appear to Share Common Disease Mechanisms

By medicilon | Featured Stories | 0 comment | 17 November, 2015 |

    Researchers at the University of Edinburgh and an international team of colleagues report that brain disorders that cause intellectual disabilities and autism spectrum behaviors may share common defects despite having different genetic causes. Two models of intellectual disability in mice were found to have demonstrated that they share similar disease mechanisms.       The scientists discoveredRead more

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  • Home
  • About
    • Medicilon Overview
    • Executive Team
    • CEO Message
    • Corporate Culture
    • Company History
    • Honor
  • Services
    • Integrated Projects
      • Antibody-Drug-Antibody (ADC)
      • Preclinical Research Services
      • IND Filing
      • Bio Drug Development
      • Chemical Drug Development
      • Chemical Compound Druggability Assessment
      • Molecular Imaging & Radiochemistry
      • OINDP Development
      • Preclinical Ophthalmic Research Platform
    • Pharmacology Services
      • Cancer Xenograft Models
      • Orthotopic Models
      • Syngeneic Mouse Models
      • Transgenic Mouse Model
      • Humanized Mouse Model (hPBMCEngrafted)
      • PDX Model
      • Digestive System Models
      • Neurological Disorders Models
      • Metabolic Disease Models
      • Inflammation & Immunological Disease Models
      • Other Disease Models
    • Chemistry Services
      • Medicinal Chemistry Services
      • Synthetic Chemistry
      • Process Development Services
      • Analytical Chemistry
    • Drug Formulation
      • Pre Formulation Development
      • Analytical Development
      • Formulation Development Services
      • Generics Consistency Evaluation
      • Research on Quality Control
      • Clinical Trial Material
      • OINDP Development
    • Biology Services
      • Discovery Biology Services
      • Recombinant Protein Services
      • Computational Biology & Molecular Modeling
      • Crystallization & Structural Determination
      • Kinase Services
      • SeMet Media Sales
    • Bioanalytical Services
      • Large Molecule Bioanalysis
      • Small Molecule Bioanalysis
    • Pharmacokinetic Services
      • In Vivo Assays
      • In Vitro Assays
    • Drug Safety Evaluation
      • Inhalation Toxicity Assessment
  • Customer
    • Customer Reviews
    • New Models of Collaboration
    • Intellectual Property Protection
    • Download Center
  • Careers
  • News
    • Medicilon Events
    • Media Coverage
    • Featured Stories
  • Contact
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