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Polypeptide is a chemically active substance ubiquitous in organisms. It is a type of compound composed of amino acids connected by peptide bonds. Compared with other chemical drugs and biotechnology drugs, peptide drugs have significant activity, strong specificity, and receptors. The affinity is good, the toxicity is weak, and it is generally not easy toRead more

New computational strategies reported that might help realize the promise of peptide-based drugs. Peptides are similar to protein molecules, but differ in their smaller size, structure and functions. In addition, peptides such as cyclosporine are stable like small molecules and selective like antibodies. The scientists explain that naturally occurring peptides that might serve as scaffoldsRead more

Peptides should make ideal drug molecules as they display high target affinity and selectivity, low inherent toxicity, and are easy to synthesize. Unfortunately, peptides also have a short half-life in the body, partly due to enzyme degradation, but primarily because their small size means that they are filtered out of the blood by the kidneys,Read more