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What is Car-T Cell Therapy?

Chimeric antigen receptor T cell (CAR-T) refers to the transfer of genetic material with specific antigen recognition domain and T cell activation signal into T cells through gene modification technology, so that T cells can be transformed into T cells. It is activated by directly binding to specific antigens on the surface of tumor cells, directly killing tumor cells by releasing perforin, granzyme B, etc., and at the same time, it also recruits human endogenous immune cells to kill tumor cells by releasing cytokines, so as to achieve therapeutic effect. It can also form immune memory T cells to obtain a specific long-acting mechanism against liver tumors.