Integrated Solutions

Medicilon can provide detection services for cytokines and biomarkers for the majority of pharmaceutical R&D personnel. Its biological analysis department has complete infrastructure and advanced instruments and equipment. It has high-end technology platforms such as flow CBA, MSD and Luminex systems, which can detect various single plex or multiple forms of cytokines and biomarkers.

The MetID team of Medicilon is composed of experienced scientists. We provide fast and reliable in vivo and in vitro MetID and reactive metabolite capture services. We also support new drug screening and domestic and foreign IND filings. Since the establishment of MetID team, Medicilon has successfully completed a large number of different types of research projects for the clients, including the challenging peptide MetID research.

We utilize medicinal chemistry and computational chemistry to design and synthesize drug-like templates and libraries of compounds to increase our clients' compound collections. The annual capacity of library production is more than 100,000 compounds.

In the research and development process of innovative drugs, the chemical process research of drugs plays a pivotal role. During the synthesis process to the scale up process in the laboratory, it is not only about output, but also various errors and risks. Therefore, in the development of innovative drugs, the assessment of the safety of chemical processes and equipment is extremely important.

Medicilon's streaming technology platform is committed to exploring and insight into the progress of tumor immune targeted therapy drugs, and providing accurate and reliable test prediction data in the early development stage. Our team has rich experience in experimental operation, streaming method development and data analysis, and every scientists could be independently responsible for the project. The platform is equipped with powerful flow cytometers of different brands such as BD and Bio-Rad. The newly introduced high-parameter BD FACSymphony A5 flow cytometer is equipped with five lasers and 30 parameters, which can enable up to 28 colors at the same time to meet clients' special scientific research and analysis needs.

Medicilon's preclinical pharmacology and toxicology research team is equipped with a professional send format conversion team, and has established a send data conversion platform that is fully mature in terms of software, technology, specification and quality, so as to realize accurate data conversion and provide a good environment for electronic data submission. In 2020 alone, it has helped customers complete 14 send data conversion projects, of which 3 new drug projects have obtained clinical licenses from FDA.

The solid screening platform of Medicilon process department strictly complies with the registration regulations and regulatory requirements of China NMPA, FDA and other regulatory authorities, studies and controls the solid morphology of drug molecules in API and preparations, and can formulate the optimal screening strategy according to the material characteristics, including but not limited to crystallization method, solvent selection and ion selection.