ABOUT
- Cytokines are proteins or polypeptides that are secreted by activated immune cells and some stromal cells to mediate and regulate immune and inflammatory responses. Cytokine detection has important value in disease diagnosis, basic immune research and cytokine therapy monitoring. For the detection of cytokines, it can not only detect the concentration of cytokines in peripheral blood, but also stimulate lymphocytes to secrete cytokines by in vitro culture, and amplify the stimulating effect of drugs on immune cells. Thus, it can predict the potential risk of drugs that may cause cytokine release syndrome, and can also determine the minimum expected biological effect level and choose a reasonable and safe starting dose.
- Biomarkers are indicators that can determine the occurrence, development and prognosis of diseases, and play an important role in early diagnosis, disease prevention, drug target confirmation, and drug response. Biomarker detection can provide insight into the mechanism of action or resistance of new drugs in disease models.
- Medicilon could provide cytokine and biomarker detection services for the global pharmaceutical communities. Medicilon's Bioanalytics Department has complete infrastructure and state-of-the-art instruments and equipment, and our high-end technology platforms such as flow CBA, MSD, and Luminex system could perform various single plex or multiplex multi-form cytokine and biomarker detection. Whether it is the early screening of a large number of candidate cytokines and biomarkers, or the large-scale validation of specific factors and biomarkers, Medicilon's Bioanalytics Department could provide suitable technology platforms and services to meet the R&D needs.
Medicilon's Cytokine and Biomarker Detection Technology Platform- Luminex multiplex Assay;MSD multiplex Assay;FACS CBA multiplex Assay;AlphaLISA;Single plex ELISA ,etc.
Types of Cytokine Testing Services- Interleukin；IFN（Interferon）; TNF（Tumor necrosis factor）;CSF; TGF; Chemokine; Growth factor,etc.We have accumulated rich experience in cytokine detection. We could provide a comprehensive index detection services according to the clients' needs.
Service Areas for Cytokine and Biomarker Detection- Tumor Research: Tumor Marker Detection, HPV Detection; Vaccine Research; Drug Efficacy Evaluation, Drug Development; Concentration Detection of Cytokines, Inflammatory Factors, Chemokines, Enzymes, etc.; Quantitative analysis of phosphorylated proteins and apoptosis-related proteins in cell signaling; Autoimmune function analysis, etc.; Epidemiological Monitor; HLA Typing Test; Cardiovascular Disease Research; Diabetes and Metabolic Disease Research; Signal Pathway Research; Gene Mutation Research, etc.
Instrument- Bio-Plex 200(Luminex 200); MESO Sector s600; FACS; MD SpectraMax M2/M4/M5; PE EnVision; Gyros,etc.
