ABOUT
Drug Discovery Plarform
Drug discovery is the initial stage of drug research and development. Through early research, the genetic functions and targets of target diseases are selected and confirmed, the lead compounds are screened and optimized, and the druggability studies such as early safety screening and drug modification are carried out to obtain druggability candidate compounds.
Pharmaceutical Research
Pharmaceutical research mainly includes APIs and preparation research, quality control and stability study, etc. Medicilon has a wide experience in pharmaceutical research services such as green enzyme chemistry, API quality research, insoluble innovative drug technology, and high-end preparations.
Preclinical Research Services
Medicilon's preclinical research services consist in three major parts: pharmacokinetics, disease transplantation models and drug safety evaluation. Our preclinical research services cover all of the aspects including design, in vivo studies, sample analysis, professional data analysis, IACUC review, and the preparation of application materials.
Chemical Drug Development
Medicilon offers the one-stop shop integrated chemical drug R&D services including customized synthesis, medicinal chemistry, focused library preparation and process chemistry. Either in FTE or integrated project team arrangement, our chemistry team has helped clients discover novel and potent chemical series.
Pharmaceutical Research CDMO
The Medicilon Process Department is deeply involved in the entire industrial chain system of the R&D, procurement and production, from preclinical small-scale synthesis route optimization, process development and scale-up, process validation, quality research to commercial production.
CDMO Service Platform
Medicilon has constructed the GMP Drug Products Pilot Plant to meet the rising needs for innovative medicine R&D, production, packaging, inspections and stability tests. We are aiming for qualified CDMO services for clients with requirements for the development of innovative medicine.
Translational Medicine Platform
The Medicilon translational medicine platform has an experienced professional technical team, starting from the mechanism of action of drug targets and the clinical application of biomarkers, based on the discovery and validation of biomarkers, combining a variety of different technology platforms and state-of-art instruments, and creating multiple bioanalytical methods, to reduce the cost and time of drug R&D, and provide diverse and efficient services for different types of drugs, different kinds of pharmaceutical companies and projects at different R&D stages.
Why choose Medicilon?- The Process From Target To PCC
- Service Models
Fee For Service (FFS)
Fixed price quoted for specific synthesis of a molecule, series or library Fixed price quoted for specific services, e.g. chiral separation, fragment-based screening CMC work for IND application and IND investigation Non-GMP and GMP scale-up, commercial production of API and intermediatesFull Time Equivalent (FTE)
Dedicated full time employees to deliver defined projects Focused team(s) with well- organized structure Flexibility to change team size and composition Flexibility to reprioritize targets/project directionIntegrated Service (INT)
From target to IND enabling Drug design and synthesis Drive the project via Medicilon Includes hit to lead, lead optimization, candidate selection and beyond Milestone payments Dedicated teams of chemistry, biology, DMPK, CMC IND registration in China and USA
