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Top 10 Global CDMO Enterprises| Top 10 Global Clinical Research Organizations in 2021| The Meaning of IND, NDA and ANDA
Jun 12,2023
Medicilon's GLP-1 New Drug R&D Service
In the formulation of GLP-1 integrated research plan, Medicilon has in-depth communication with customers. Medicilon provides GLP-1 drug discovery, CMC research (API + formulation), pharmacodynamics research, PK study, GLP-1 safety evaluation and other services.
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Medicilon's GLP-1 New Drug R&D Service
May 19,2023
Antibody-oligonucleotide conjugates (AOCs) —A new wave of drug conjugates
Antibody-Oligonucleotide Conjugates (AOCs) represent an emerging class of functionalized antibodies that have already been used in a wide variety of applications. Following let us introduce the evolution of nucleic acid delivery technologies,Conjugation mechanism of AOC.
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Antibody-oligonucleotide conjugates (AOCs) —A new wave of drug conjugates
May 08,2023
Medicilon Flow Sorting Platform
Based on the technical basis of flow cytometry, the Medicilon flow sorting platform is widely used in scientific research and work in immunology, cell biology, oncology, hematology, drug development, and environmental testing. Medicilon flow cytometry team has extensive experience in experimental operation, flow sorting method development and data analysis.
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Medicilon Flow Sorting Platform
May 08,2023
【Expert Report】Dr. Xingquan Ma: Medicinal Chemistry in Small Nucleic Acid Drug Discovery
On March 24, 2023, Dr. Xingquan Ma, SVP of the Chemistry Department of Medicilon, gave a report titled "Medicinal Chemistry in Small Nucleic Acid Drugs Discovery" during the IDC2023 4th Chemical New Drug and Improved New Drug R&D Forum. Medicilon can provide monomer synthesis and modification; oligonucleotide synthesis; delivery system synthesis and synthesis of oligonucleotide conjugates.
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【Expert Report】Dr. Xingquan Ma: Medicinal Chemistry in Small Nucleic Acid Drug Discovery
May 04,2023
A Nickel-Catalyzed Reductive Alkylation of Aryl Bromides and Chlorides for Sp3-Sp2 Bond Formation
In 2012, a nickel-catalyzed reductive alkylation method of aryl bromides and chlorides was reported. Under the optimized conditions, a variety of aryl and vinyl bromides as well as active aryl chloride can be reductively coupled with alkyl bromides in high yields.
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A Nickel-Catalyzed Reductive Alkylation of Aryl Bromides and Chlorides for Sp<sup>3</sup>-Sp<sup>2</sup> Bond Formation
Mar 03,2023
Whole-Process of Antibody Drug Development - Facilitate IND Declaration of Biological Drugs
The Medicilon antibody development platform has been deeply involved in the field of antibody drug research and development and their technical services include the ADA antibody development technical services and druggable antibody development technical services, ADA-free polyclonal antibody development, ADA mouse hybridoma monoclonal antibody development, phage display rabbit monoclonal antibody development services, mouse monoclonal antibody development technical services, mouse/rabbit single B cell antibody development technical services and other projects.
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Whole-Process of Antibody Drug Development - Facilitate IND Declaration of Biological Drugs
Feb 24,2023
Beautiful Chemistry-Photoinduced Alkene Cleavage Using Nitroarenes
The oxidative cleavage of olefins is an important transformation in organic synthesis to obtain carbonyl functional groups such as ketones and aldehydes. Medicilon has integrated emerging methods of green chemistry into its services, using currently popular photoredox chemistry, electrochemisty, catalyst screening, continuous reactions, etc., to provide our customers with high-quality economic solutions.
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Beautiful Chemistry-Photoinduced Alkene Cleavage Using Nitroarenes
Feb 17,2023
Come, Chat with ChatGPT regarding CRO
Almost overnight, the whole city chatted about ChatGPT. While people are admiring the omnipotence of AI, people also worry that their jobs will be taken away by AI one day...
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Come, Chat with ChatGPT regarding CRO
Feb 17,2023
Market Prospects, Development Challenges and Countermeasures of Oligonucleotide Drugs
In recent years, with the advancement of related research and technology, nucleic acid drugs have ushered into rapid development, and the number of nucleic acid drugs approved for the global market is increasing yearly.
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Market Prospects, Development Challenges and Countermeasures of Oligonucleotide Drugs
Feb 04,2023
World Cancer Day: Features of Popular Tumor Models in Oncology Drug Development
February 4th is the 24th World Cancer Day. Medicilon has been part of the great human effort to combat cancer since its founding in 2004. In order to better understand tumorigenesis, to foster cancer prevention and to develop novel anti- cancer therapy, Medicilon has been providing IND enabling preclinicalservice for 19 years, and has established close to 300 tumor evaluation model for R&D.
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World Cancer Day: Features of Popular Tumor Models in Oncology Drug Development