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Medicilon Human Disease Animal Model

2020-07-01
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Medicilon provides various effective animal models according to customer needs to test the effectiveness of drugs. Experimental animals include non-human primates, dogs, mice, rats, rabbits, and guinea pigs. At present, we have established a number of effective animal models, and have passed multiple verifications and long-term practical tests. At the same time, our employees’ rich experience and strong theoretical foundation can flexibly develop and build various customized models according to customer’s customization requirements to meet customer needs.

animal model

Tumor disease model

Medicilon provides various effective animal models according to customer needs to test the effectiveness of drugs. Experimental animals include non-human primates, dogs, mice, rats, rabbits, guinea pigs, and nude mice. At present, we have established a number of effective animal tumor models, and have passed multiple verifications and long-term practical tests. At the same time, our employees’ rich experience and strong theoretical foundation can flexibly develop and build various customized tumor disease models according to customer’s customization requirements to meet customer needs. see more

Type of cancer (tumor model)Cell line
Head and neck tumor modelKB, FaDu
Animal model of nasopharyngeal carcinoma
Stem cell animal model
S18, S26
Lung cancer animal modelsDMS114, NCI-H69, NCl-H146, NCl-H209, NCI-H446, NCI-H526, NCI-H1688, 95-D, A549, Calu-1, Calu-3, Calu-6, HCC827, NCI -H226, NCI-H292, NCI-H358, NCI-H441, NCI-H460, NCI-H520, NCI-H522, NCI-H1299, NCI-H1437, NCI-H1650, NCI-H1975, NCI-H1993, NCI-H2009 , NCI-H2122, NCI-H2126, NCI-H2228, PC-10, QG-56
Breast cancer animal modelsSUM159, MDA-MB-231, MDA-MB-468, Bcap-37, 2LMP, ZR-75-1, ZR-75-30
Animal model of gastric cancerMKN-45, NCI-N87, BGC-823, HGC-27, MKN-28, NUGC-3, SCH, SGC-7901, SNU-5, SNU-16, MGC-803
Animal model of pancreatic cancerAsPC-1, BxPC-3, Capan-1, Capan-2, CFPAC-1, HPAF-II, MIAPaCa-2, PANC-1
Kidney cancer animal modelACHN, OS-RC-2, 786-O
Liver cancerBel-7402, Hep-3B, Huh-7, PLC/PRF/5, QGY-7703, SK-HEP-1, SMMC-7721, HepG-2
GlioblastomaU87-MG
Colon and cecum cancersCOLO 201, COLO 205, COLO 320 DM, CW-2, DLD-1, HCT-8, HCT-15, HCT-116, HCT116 P53 K0(-/-), HT-29, LoVo, LS1034 , LS174T, LS411N, NCI-H716, RKO, SW48, SW620
Prostate cancer 22Rv1, CL-1, DU145, LNCap Clone FGC, PC-3
BladderHT-1197, HT-1376, RT4, SCaBER, SW780, T24
Ovarian cancerES-2, HO-8910PM, PA-1, SK-OV-3, OVCAR-3
Endometrium / HysterocarcinomaAN3 CA, HEC-1-A, ME-180, MFE-280
Skin cancer cellA431
MelanomaA375, B16, A2058, C32, HMCB, SK-MEL-30, MDA-MB-435s
Osteosarcoma cellsMG-63, SJSA-1
SarcomaS-180
Muscles, stripesSJCRH30
MyelomaKMS-11, KMS-26, RPMI-8226
Leukemia/lymphomaU937, THP-1, MV-4-11, HEL, TF-1a, ML-2, HL-60, L1210, K562, KARPAS-299, Daudi, Raji, Ramos, ARH-77, KMS- 12-BM, KG-1

Digestive system disease model

Medicilon provides various effective animal models (renal failure model, anemia animal model, gastric acid secretion animal model, gastric ulcer model, etc.) according to customer needs to test the effectiveness of drugs. Conventional diseases of the digestive system include: gastric acid secretion, gastric ulcer, renal failure, etc. Animal experiments are carried out in rats.

diseaseThe Digestive system disease modelThe Test animal
Renal failureThe Nephrectomy (5/6)The Rat
anemiaThe Renal failure inductionThe Rat
Gastric acid secretionThe Histamine gastric acid secretion modelThe Rat
The Pylorus ligation model of gastric acid secretionThe Rat
The Ethanol gastric ulcer modelThe Rat
Gastric ulcerAspirin gastric ulcer modelThe Rat

Endocrine and Metabolic Disease Model

Medicilon provides a variety of effective endocrine disease models and animal models of metabolic diseases according to customer needs to test the effectiveness of drugs. Conventional endocrine diseases and metabolic diseases include: diabetes, obesity, dyslipidemia, etc. Animal experiments are conducted with large mice and hamsters.

DiseaseEndocrine and Metabolic Disease ModelAnimal
DiabetesStreptozotocin DiabetesMice
Spontaneously diabeticdb/db, ob/ob mice
Obese mice induced by high-fat dietDIO mice
ObesityHereditarydb/db, ob/ob mice
Obese mice induced by high-fat dietDIO mice
Dyslipidemia High fat/cholesterolHamster

Inflammation and immune disease models

Medicilon provides various effective inflammatory disease models and animal models of immune diseases according to customer needs to test the effectiveness of drugs. Conventional inflammation and immune diseases include: acute inflammation, arthritis, experimental allergic encephalomyelitis, etc. Animal experiments are conducted with large mice. see more

Nervous system disease model
Medicilon provides a variety of effective animal models (depression animal models, Parkinson’s disease animal models, psychotic animal models, etc.) according to customer needs to test the effectiveness of drugs. Routine neurological diseases include: psychosis, Parkinson’s disease, depression, pain (central), etc. Animal experiments are conducted with large mice and guinea pigs. see more

Contact us

Email: Marketing@medicilon.com

Phone: 021 58591500

The relevant content of the above disease animal models is officially provided by Medicilon.

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