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Top 10 Global Clinical Research Organizations in 2021| ADC, precision and deep cultivation for targeted drug delivery| What are the three major in vitro pharmacokinetic research methods?
Sep 15,2021
Study on the Pharmacological Effects of Dendrobium Nobile and its Pharmacokinetics in Rats
Dendrobium nobile has a long history of medicinal use. It is a common traditional Chinese medicine. The chemical components are divided into alkaloids, glycosides, phenanthrene and bibenzyls according to the structure type. Its pharmacological effects are mainly manifested in anti-tumor, hypoglycemic and anti- Nervous system protection and other aspects. The pharmacokinetic study of dendrobine inRead more
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Study on the Pharmacological Effects of Dendrobium Nobile and its Pharmacokinetics in Rats
Sep 14,2021
DMPK and Mechanism of Drug Interaction
When treating diseases, patients often need to receive more than one drug to enhance the therapeutic effect. When multiple drugs are administered at the same time, drug-drug interaction (DDI) may occur. Drug interaction based on pharmacokinetics is one of the main ways of drug interaction, including the interaction in the four links of drug absorption,Read more
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DMPK and Mechanism of Drug Interaction
Sep 13,2021
Study on the Pharmacokinetics of Gastrodin and its Pharmacological Effects
Gastrodia is a dry tuber of the orchid plant Gastrodia elata. It is a traditional and precious Chinese medicine for calming the liver, relieving wind and relieving spasm. Gastrodin is the main active ingredient of Gastrodia. Pharmacological studies have shown that Gastrodia has sedative, anti-convulsant, anti-epileptic properties, and increases cerebral blood flow. Protect nerve cellsRead more
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Study on the Pharmacokinetics of Gastrodin and its Pharmacological Effects
Sep 10,2021
Two Breast Cancer Endocrine Therapy Drugs have Passed the Consistency Evaluation
Breast cancer is a hormone-dependent tumor. Studies have found that for breast cancer patients who are hormone receptor-positive and cannot tolerate surgical treatment, endocrine therapy has found better results. The two commonly used breast cancer endocrine therapy drugs, tamoxifen citrate tablets and anastrozole tablets, have both passed the consistency evaluation of the quality and efficacyRead more
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Sep 10,2021
The Consistency Evaluation of Generic Drugs Requires Attention to the Particle Size of API
In the development of pharmaceutical preparations, due to the different synthesis processes of API from different sources, there may be differences in their solubility, crystal form, particle size, and impurities, which may affect the consistency of the product. In the evaluation of the consistency of generic drugs, the particle size control of API should notRead more
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The Consistency Evaluation of Generic Drugs Requires Attention to the Particle Size of API
Sep 10,2021
In Vivo and in Vitro Studies of Formulation and Consistency Evaluation of Generic Drugs
In the consistency evaluation of generic drugs, it is very important to take effective measures to accurately evaluate the in vivo and in vitro relevance of drugs. Appropriate in vivo and in vitro correlation models can accurately predict the action characteristics of the drug in vivo, thereby guiding and optimizing the formulation design, establishing moreRead more
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Sep 09,2021
Construction and Supervision of GLP Laboratory
Good Laboratory Practice(GLP) is related to drug registration. It is a regulatory document that non-clinical trials used to evaluate drug safety need to comply with. Many new drugs entered the clinic after simple animal experiments showed that they had certain effects and were not very toxic. At the same time, the clinical trial was tooRead more
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Construction and Supervision of GLP Laboratory
Sep 09,2021
Gap in GLP Practice Between China and Foreign Countries
The Code of Quality Management for Non-clinical Research of Drugs, or GLP for short, is the basic principle that must be followed for pre-clinical research of drugs. It is also a fundamental measure to improve the quality of new drug research from the source and ensure the safety of drug use by the people. AfterRead more
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Gap in GLP Practice Between China and Foreign Countries
Sep 08,2021
Feeding and management of animals in GLP lab
GLP, non-clinical quality management practices for drugs, is the basic principle that drugs must follow for pre-clinical research. At present, the distance between my country's GLP organization, China GLP, and developed countries such as the United States, has gradually narrowed, and the organization that ranks first in China's GLP organization also affirms the strength ofRead more
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Feeding and management of animals in GLP lab
Sep 07,2021
Medicilon's antibody drug R&D technology platform assisted Bio-Thera Solutions, Ltd's two projects to get the clinical approvals
Recently, Bio-Thera Solutions, Ltd. (Bio-Thera)'s BAT6021 injection and BAT6005 injection of innovative drugs have been approved for clinical use, which means the new progress has been made in the field of tumor treatment. Recently, Bio-Thera Solutions, Ltd. (Bio-Thera)'s BAT6021 injection and BAT6005 injection of innovative drugs have been approved for clinical use, which means theRead more
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