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Top 10 Global Clinical Research Organizations in 2021| ADC, precision and deep cultivation for targeted drug delivery| What are the three major in vitro pharmacokinetic research methods?
Sep 07,2021
Medicilon assists Chipscreen Biosciences' CS12192 to be approved by the FDA
On August 28, 2021, the FDA recently approved the CS12192, a new drug clinical trial application for the treatment of Graft Versus Host Disease (GVHD) independently developed by Chipscreen Biosciences (Chipscreen).  Previously, the drug has obtained clinical approval in China. It is worth mentioning that Shanghai Medicilon Inc. (Medicilon) provides comprehensive preclinical research including pharmacokineticsRead more
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Medicilon assists Chipscreen Biosciences' CS12192 to be approved by the FDA
Sep 07,2021
GLP requirements for animal lab environment and facilities
Animal experiment facilities refer to the sum of buildings, equipment, and operation management for the purpose of research, experimentation, teaching, biological products and pharmaceutical production, etc., for the breeding and experimentation of experimental animals. Its management is very important for applying for GLP certification. Companies that rank high in China's GLP organization will undoubtedly payRead more
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GLP requirements for animal lab environment and facilities
Sep 07,2021
Analysis of the role of GLP regulations and ideas
The pharmaceutical production quality assurance system-Pharmaceutical Non-clinical Research Quality Management Practices (GLP) is the key to improving the quality of pharmaceuticals. It is a common practice for non-clinical drug safety evaluation work in the world, and it is also the international toxicology data exchange and mutual recognition of information. The basics. The GLP laboratories ownedRead more
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Analysis of the role of GLP regulations and ideas
Sep 07,2021
Why should GLP regulations be implemented in new drug research?
GLP, Good Laboratory Practice, is a standard for safety evaluation experiments conducted on medicines, pesticides, food additives, cosmetics, etc., involving all aspects of laboratory work. For drug development, the implementation of GLP in pharmacology and toxicology research can guarantee the reliability, completeness and repeatability of experimental results. The top institutions in the ranking of ChineseRead more
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Why should GLP regulations be implemented in new drug research?
Sep 06,2021
Screening and optimization of lead compounds for new drug development
Lead compound is a compound with biological activity and unique chemical structure. Lead compound optimization is the process of transforming active compounds into drugs through structural transformation, and evolving non-drugs into candidate drugs or new drugs. It is an important content of new drug development. In the process of new drug research, a large numberRead more
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Screening and optimization of lead compounds for new drug development
Sep 06,2021
The Pharmacological Effects of Imperatorin and its Preformulation Study
The pharmacological studies of imperatorin extracted from the dried root of the Umbelliferae plant Angelica dahurica have various effects such as antibacterial, anti-asthmatic, anti-allergic, dilation of blood vessels, and inhibition of tumor cell proliferation. Lipid microspheres and liposomes are drug carriers prepared from natural lipid materials such as phospholipids and cholesterol. With this carrier, drugsRead more
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The Pharmacological Effects of Imperatorin and its Preformulation Study
Sep 06,2021
Analysis of the Characteristics of Aerosol and Preformulation Research
Aerosol is a dosage form of medicine. It is a dispersion system composed of fine liquid droplets or solid particles (dispersed inner phase) in air or mixed gas (dispersed outer phase). The dispersed ions are extremely small, and the diameter is from 1 to hundreds of nanometers. , Generally divided into high, medium and lowRead more
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Analysis of the Characteristics of Aerosol and Preformulation Research
Sep 03,2021
Application of Western Blot Analysis in Studying the Proliferation of NM23B Gene Cells
NM23 is a tumor metastasis suppressor gene, which has regulatory functions on cell proliferation, differentiation and ontogeny. At present, 10 subtypes of NM23 have been found, and the more thorough research is NM23A and NM23B. Western blot analysis shows that NM23B has hepatocyte proliferation effect on SD rats cultured in vitro. Western blot analysis, alsoRead more
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Application of Western Blot Analysis in Studying the Proliferation of NM23B Gene Cells
Sep 03,2021
Western blot analysis technique in detecting protein expression level
Lung cancer is one of the most harmful malignant tumors. To explore the pathogenesis of lung cancer and find new targets for anti-tumor therapy are the hotspots and difficulties in the current research on lung cancer treatment. Studies have found that aquaporin 4 (AQP4) is highly expressed in lung cancer cells, and knocking down AQP4Read more
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Western blot analysis technique in detecting protein expression level
Sep 02,2021
Factors Influencing the Dissolution of Solid Dosage Forms
In theory, in vivo drug testing is the most important and reliable basis for evaluating drugs. However, in the development of oral solid dosage forms, the method of measuring bioavailability is used to screen and evaluate each new prescription and process, which is time-consuming and costly. money. Although the results of in vivo and inRead more
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Factors Influencing the Dissolution of Solid Dosage Forms