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Top 10 Global Clinical Research Organizations in 2021| Medicilon Pharmacokinetic Services for First-in-Class Ubiquitination Inhibitor Development| ADC, precision and deep cultivation for targeted drug delivery
Sep 06,2021
Screening and optimization of lead compounds for new drug development
Lead compound is a compound with biological activity and unique chemical structure. Lead compound optimization is the process of transforming active compounds into drugs through structural transformation, and evolving non-drugs into candidate drugs or new drugs. It is an important content of new drug development. In the process of new drug research, a large numberRead more
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Screening and optimization of lead compounds for new drug development
Sep 06,2021
The Pharmacological Effects of Imperatorin and its Preformulation Study
The pharmacological studies of imperatorin extracted from the dried root of the Umbelliferae plant Angelica dahurica have various effects such as antibacterial, anti-asthmatic, anti-allergic, dilation of blood vessels, and inhibition of tumor cell proliferation. Lipid microspheres and liposomes are drug carriers prepared from natural lipid materials such as phospholipids and cholesterol. With this carrier, drugsRead more
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The Pharmacological Effects of Imperatorin and its Preformulation Study
Sep 06,2021
Analysis of the Characteristics of Aerosol and Preformulation Research
Aerosol is a dosage form of medicine. It is a dispersion system composed of fine liquid droplets or solid particles (dispersed inner phase) in air or mixed gas (dispersed outer phase). The dispersed ions are extremely small, and the diameter is from 1 to hundreds of nanometers. , Generally divided into high, medium and lowRead more
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Analysis of the Characteristics of Aerosol and Preformulation Research
Sep 03,2021
Application of Western Blot Analysis in Studying the Proliferation of NM23B Gene Cells
NM23 is a tumor metastasis suppressor gene, which has regulatory functions on cell proliferation, differentiation and ontogeny. At present, 10 subtypes of NM23 have been found, and the more thorough research is NM23A and NM23B. Western blot analysis shows that NM23B has hepatocyte proliferation effect on SD rats cultured in vitro. Western blot analysis, alsoRead more
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Application of Western Blot Analysis in Studying the Proliferation of NM23B Gene Cells
Sep 03,2021
Western blot analysis technique in detecting protein expression level
Lung cancer is one of the most harmful malignant tumors. To explore the pathogenesis of lung cancer and find new targets for anti-tumor therapy are the hotspots and difficulties in the current research on lung cancer treatment. Studies have found that aquaporin 4 (AQP4) is highly expressed in lung cancer cells, and knocking down AQP4Read more
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Western blot analysis technique in detecting protein expression level
Sep 02,2021
Factors Influencing the Dissolution of Solid Dosage Forms
In theory, in vivo drug testing is the most important and reliable basis for evaluating drugs. However, in the development of oral solid dosage forms, the method of measuring bioavailability is used to screen and evaluate each new prescription and process, which is time-consuming and costly. money. Although the results of in vivo and inRead more
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Factors Influencing the Dissolution of Solid Dosage Forms
Sep 02,2021
Method for Checking the Water Content in the Development of Solid Dosage Forms
Medicines are the foundation for human survival and social development, and are related to people's lives, health and safety. In the research and development of solid dosage forms, some drugs need to be treated with water, and some need to be added with a certain amount of liquid excipients. Improper operation will affect the qualityRead more
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Method for Checking the Water Content in the Development of Solid Dosage Forms
Aug 31,2021
Selection of Excipients for Oral Solid Dosage Process Research
It is well known that medicine is a special commodity that can meet people's needs for treatment and rescue. However, pharmaceutical preparations involve a lot of content in the process of research and development. In drug development, it may be affected by such things as low level of drug development, more repetitive drugs, and drugRead more
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Selection of Excipients for Oral Solid Dosage Process Research
Aug 31,2021
What are the methods for improving yeast two-hybrid technology?
Yeast two-hybrid technology, as the main method of studying protein interaction, occupies a pivotal position in large-scale protein interaction research, and has become an important experimental method in the field of molecular biology research. Therefore, many biological companies provide everything from constructing hybrid libraries to One-stop yeast two-hybrid service for library screening. However, the molecularRead more
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What are the methods for improving yeast two-hybrid technology?
Aug 31,2021
Application of Yeast Two-hybrid Technology in Screening Drugs and Finding Drug Targets
The yeast two-hybrid system is an important technical means for studying protein-protein interactions, and is now also being used in high-throughput screening of interacting proteins and other related molecules. Yeast transformation is simple and efficient. After the yeast two-hybrid library is constructed, it is relatively easy to directly screen out positive clones that interact betweenRead more
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Application of Yeast Two-hybrid Technology in Screening Drugs and Finding Drug Targets