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Top 10 Global Clinical Research Organizations in 2021| Medicilon Pharmacokinetic Services for First-in-Class Ubiquitination Inhibitor Development| ADC, precision and deep cultivation for targeted drug delivery
Aug 18,2021
Do you know about western blotting?
IBT and LIA The Western blot detection technology currently used is not the original Western blot (IBT) but an optimized and improved method. western blotting Traditional Western Blotting (IBT): the protein is separated and purified by electrophoresis and transferred to a nitrocellulose membrane, and then autoimmune serum is used as a probe to react withRead more
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Do you know about western blotting?
Aug 18,2021
Western Blot Detection
The Biology Department of Shanghai Medicilon has extensive experience in the field of in vitro biology, through enzyme level determination, cell level determination, cell biology, biochemistry, in vitro isotope determination, stable cell line establishment, gene knockout, RNAi and MicroRNA Technology, etc., to provide a complete set of biological services. In cell biology research, sometimes itRead more
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Western Blot Detection
Aug 11,2021
Pharmaceutical Research of Innovative Drug IND Application
The development of innovative drugs is an extremely exploratory research process, which usually starts from the unknown and carries out drug screening and discovery based on unmet clinical needs. Different from generic drugs, research on innovative drugs is gradually carried out with different stages. The depth of each stage of research usually corresponds to theRead more
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Pharmaceutical Research of Innovative Drug IND Application
Aug 10,2021
Protein Purification Methods and Comparison of Advantages and Disadvantages
The separation and purification of proteins is more complicated. Proteins extracted from cells or proteins obtained from solutions containing proteins through precipitation, gradient centrifugation, salting out and other methods often contain impurities. These impurities must be removed while maintaining the biological characteristics of the protein. For the chemical activity, such as the catalytic activity ofRead more
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Protein Purification Methods and Comparison of Advantages and Disadvantages
Aug 10,2021
What are the Methods of Protein Separation and Purification?
The separation and purification of protein is an important part of biochemistry. It is a method of separating and purifying the desired target protein from the mixture using bioengineering technology. There are many protein separation companies. Medicilon is a preclinical drug development company (CRO) that can provide protein separation and purification technology services. There areRead more
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What are the Methods of Protein Separation and Purification?
Aug 10,2021
Protein Characteristics and Protein Separation Technology
Proteins generally exist as complex mixtures in tissues or cells, and each type of cell contains thousands of different proteins. The separation and purification of proteins is an arduous and arduous task. So far, there is no single or a set of ready-made methods that can extract any kind of protein from a complex mixture,Read more
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Protein Characteristics and Protein Separation Technology
Aug 09,2021
Things about IND application
Introduction to IND IND, Investigational New Drug, generally refers to a new drug that has not been approved for marketing and is undergoing clinical trials at various stages. In actual applications, IND or CTA (clinical trial application) has become synonymous with pre-marketing human clinical trials. The IND application may be one or a sequential groupRead more
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Aug 09,2021
What is IND, NDA, ANDA?
The FDA new drug review process includes two processes: ind filing for new drug clinical trial application and new drug application NDA application. After the applicant completes the preclinical study of the new drug, he can submit an IND filing to the FDA. If the FDA does not object within 30 days of receipt ApplicantsRead more
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What is IND, NDA, ANDA?
Aug 06,2021
General Principles and Method Selection of Protein Purification
With the development of molecular biology, more and more scientific researchers have mastered various experimental techniques of molecular biology, and developed a complete set of kits to make gene cloning and expression easier and easier. However, the upstream work of molecular biology is often not the ultimate goal. The key to molecular cloning and expression
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General Principles and Method Selection of Protein Purification
Aug 05,2021
Cell and Gene Therapy: a New Direction for Innovative Therapies
Cell therapy Cell therapy is the introduction of new cells into a tissue to stimulate the body’s ability to heal itself and repair or rebuild a strong immune system in order to treat disease. Cell therapy is mainly divided into stem cell therapy and immune cell therapy. Stem cells therapy Stem cells have the abilityRead more
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