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Top 10 Global Clinical Research Organizations in 2021| ADC, precision and deep cultivation for targeted drug delivery| What are the three major in vitro pharmacokinetic research methods?
Aug 02,2021
Drug Safety Evaluation
Medicilon has a professional team and practical experience in drug safety evaluation, and can provide high-quality data and fast turnaround to support various drug safety evaluation studies. Toxicology studies can be performed in accordance with non-GLP or GLP standards. Our research platform has been rated as the Shanghai R&D public service platform. Medicilon drug safetyRead more
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Drug Safety Evaluation
Aug 02,2021
Why should GLP be implemented in new drug research?
GLP, Good Laboratory Practice, is a standard for safety evaluation experiments conducted on medicines, pesticides, food additives, cosmetics, etc., involving all aspects of laboratory work. For drug development, the implementation of GLP in pharmacology and toxicology research can guarantee the reliability, completeness and repeatability of experimental results. The top institutions in the ranking of ChineseRead more
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Why should GLP be implemented in new drug research?
Jul 31,2021
Bioanalytical Research Method
With the rapid development of the pharmaceutical industry, the research of biotechnology drugs has also entered a higher level of platform. Biotechnology drugs refer to therapeutic drugs produced through recombinant DNA technology or other innovative biotechnology-based biotechnology, which mainly include cytokines, plasminogen activators, recombinant plasma factors, growth factors, antibodies, vaccines and oligonucleotide drugs It isRead more
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Bioanalytical Research Method
Jul 31,2021
Biological analysis challenges of chemical drugs
New drug research and development is accompanied by high risks, high investment, and low returns. During this period, two important issues must be repeatedly verified: Is it safe and effective? Pharmaceutical R&D workers need to conduct systematic research on drugs through various preclinical and clinical trials to reveal or confirm the effects of test drugs,Read more
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Biological analysis challenges of chemical drugs
Jul 31,2021
Discovery of hit compounds
The discovery of hit compounds determines the starting point of the entire drug discovery process and is of vital importance. The confirmation stage of the hit compound is as follows: Exclude compounds with potential reactivity, interference with testing, or self-aggregation. Repeated activity test: For the selected target, the active compound obtained by high-throughput screening isRead more
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Jul 30,2021
Pre-formulation Research of Generic Drugs
The purpose and importance of pre-prescription research The purpose of the Pre-formulation research is to provide the basis for the prescription process design, and to provide a clear mechanism of targeted solutions to the problems in the prescription process research. The quality characteristics of the final product are largely determined by the nature of theRead more
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Pre-formulation Research of Generic Drugs
Jul 30,2021
Preformulation Research for New Drug Development
Generally speaking, the several necessary stages of new drug development are: 1) pre-formulation research; 2) dosage form selection, which is to determine the appropriate dosage form according to the physical and chemical properties of the drug, clinical treatment and application needs; 3) prescription research, That is, according to the physical and chemical properties of theRead more
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Preformulation Research for New Drug Development
Jul 30,2021
The Value and Importance of Preformulation Research
The purpose of preformulation research is to provide a basis for preformulation process design, and to provide clear mechanism and targeted solutions to problems arising in the research of preformulation process. The quality characteristics of the final product are largely determined by the properties of the drug substance. Although there are many ways to optimizeRead more
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The Value and Importance of Preformulation Research
Jul 30,2021
Preformulation Research
Medicilon has been offering high quality analytical testing services to the pharmaceutical industry for decades. We offer a wide range of quality control testing services to support drug research, registration and production. Biopharmaceutical companies also use many of the same services and Medicilon has also added new services to accommodate their unique needs (detailed inRead more
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Preformulation Research
Jul 29,2021
Metabolites Modify Proteins
Metabolism is the most basic characteristic of life activities. On the one hand, metabolism can directly meet the material needs of individual growth and development through the synthesis of energy and biomacromolecules. On the other hand, more and more studies have shown that metabolites accumulated during metabolism, such as lactic acid, succinic acid, coenzyme A,Read more
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Metabolites Modify Proteins