In the research and development process of innovative drugs, the chemical process research of drugs plays a pivotal role. During the synthesis process to the scale up process in the laboratory, it is not only about output, but also various errors and risks. Therefore, in the development of innovative drugs, the assessment of the safety of chemical processes and equipment is extremely important.
In January 2017, the State Administration of Work Safety issued the instructions and guidelines on strengthening the safety risk assessment of fine chemical reactions.
Enterprises involved in the key supervision of hazardous chemical processes and Grignard reactions, intermittent and semi-batch reactions of metal organic synthesis reactions, in any of the following situations, must carry out a reaction safety risk assessment:
- The new technology and formula used for the first time in China for industrial production and the new process introduced for the first time from overseas and the reaction safety risk assessment has not been carried out.
- The existing process route, process parameters or device capabilities are changed, and the safety risk assessment report is not filed.
- Production safety accidents have been occurred due to reaction process issues.
Adhering to “Innovation-Driven, Quality First”, Medicilon has established a laboratory research platform focused on evaluating the safety of chemical processes to provide clients with customized, accurate and reliable testing data and safety assessments.
Safety Assessment Process
Safety Assessment Laboratory
Automatic Reaction Calorimeter RC1mx
Model: METTLER TOLEDO RC1mx
RC1 Reaction Calorimetry Test Data list
Differential Scanning Calorimeter DSC
DSC Test Data
Decomposition Heat Evaluation List
Adiabatic Accelerating Calorimeter ARC
ARC Test Chart and Data