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Biology Research

Biology Research

Our Biology Department boasts a variety of technical solutions, professional scientific research teams, various advanced instruments and biological laboratories. Medicilon has broad experience in fields such as molecular biology, cell biology, in vitro biology, and structural biology.

With our technical platforms such as enzyme level and cell level measurement platforms, we can enable our clients to select compounds and research their properties, action mechanism and provide bio-marker analysis, thus ensuring the effective implementation of our clients' projects and helping promote the process of drug R&D.

Biology Service Model & Advantages
  • biology.wenp
    biology.wenp
    Biology Division has been dedicated to drug discovery services for over 19 yearsServing over 300 clients annuallyOver 1000 screening methods established, generating over 2 million data points per yearConducted conformational studies for more than 200 targetsCell library with over 400 tumor cell lines for drug sensitivity testingRich knowledge base with more than 50 new experimental methods and 5 new platforms per yearClinical biomarker detection system has been gradually improved, with the ability to detect biomarkers in human blood and tissue samples, and NanoString nCounter tissue mRNA detection platform is under preparation
Feature Platform
  • Kinase Screening PlatformEnzymatic/Molecular Interaction Screening PlatformCell Screening PlatformSmall Nucleic Acid Platform
Structural Biology

Our Structural Biology Laboratory is equipped with molecular cloning room and a drug discovery and selection solution based on protein crystallography, supporting drug development based on structures and from new targets determination to final structural determination.

Our structural biology solution is one of the earliest established structural biology laboratories in China, and has been recognized as providing an important new drug R&D solution by the Shanghai Municipal People's Government.

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Cell Biology

Medicilon can offer Cell Assay Analysis and Radioisotope Analysis for clients.

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Enzymology & Molecular Interactions

Medicilon Biology Department has rich experience in the field of in vitro biology, and offers a complete set of biological services including enzyme level measurement, cell level measurement, cell biology, biochemistry, isotope measurement in vitro, establishment of stable cell lines, gene knockout, RNAi and MicroRNA technology.

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Antibody Discovery

Antibody discovery technology plays a vital role in drug development, mainly discovering antibodies with specific binding activity by screening antibody libraries or antibodies obtained from animal immunization. This can help researchers accelerate the drug development process. It can also help researchers better understand diseases, including disease pathogenesis and discovering new therapeutic targets.

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Translational Medicine

Medicilon translational medicine platform is committed to providing global partners with comprehensive biomarker discovery, target integrated solutions for point-of-care verification, companion diagnostic development, and commercial testing.

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Anti-drug Antibody Preparation

Medicilon has rich experience in ADA development and has successfully delivered more than 100 projects. Medicilon can provide high-affinity and specific polyclonal anti-drug antibody development services with short development cycles and low costs.

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Hybridoma Technology
Medicilon biology department has established an antibody drug development platform, and our team members have more than 10 years experience in custom antibody production. Medicilon's hybridoma R&D services can provide a variety of immunization methods (proteins, peptides, small molecules, whole cells) to meet with the client's needs.
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Nanobody Preparation
Medicilon provides camelid VHH antibody library construction services, including antigen preparation, immunization, construction of antibody library bacteria, nanobody selection, ELISA verification and other related experiments.
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NanoString nCounter Detection Platform
NanoString technology has been widely applied to the frontier fields of biopharmaceutical, including the validation of high-throughput gene expression results, gene expression profiling studies, gene regulatory network research, and clinical disease molecular classification, diagnosis and prognosis.
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Coagulation Pathway Studies In Vitro

The drug development of anticoagulants and procoagulant agents are the most important for the treatment of thrombotic and hemorrhagic disorders, including cardiovascular diseases. So the screening platform in vitro for anticoagulants and procoagulant drugs plays a crucial role in the early stage of drug discovery. Medicilon provides studies of coagulation pathways, offering clients high-quality screening data to support drug structure-activity relationship studies.

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