Over 19 years of experience in R&D

01 Drug Discovery

Chemistry Research

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Full Time Equivalent(FTE)

Computational Biology & Molecular Modeling

Enzymology & Molecular Interactions

Early Pharmacokinetics

02 Pharmaceutical Research

Intermediates

Active Pharmaceutical Ingredients

Route Selection

Production Process Optimization

Clinical Sample Production

Impurity Traceability & Control

Generic Drug Process Study & Filing

Innovative Drug Process Study & Filing

Pharmaceutical preparation

Preformulation Study

Formulation Technology Research

Preparation Quality Research

Laboratory-scale Preparation Testing

Pilot-scale Preparation Testing

GMP-based Clinical Sample Production & Packaging

Formulation Stability Study

Consistency Evaluation

Analytical Method Development and Quality Control

CMC Filings

03 Preclinical Research

Pharmacology & Pharmacodynamics

Tumor Models

Digestive System Disease Models

Endocrine & Metabolic Disease Models

Inflammatory & Immune Diseases Models

Neural System Disease Models

Other Disease Models

Ocular Diseases Models

Cardiovascular Model

Drug Safety Evaluation

Pharmacology & Toxicology Study

Safety Pharmacology

Histopathological Study

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Drug Safety Evaluation Basic Information

Toxicokinetics

Pharmacokinetics

In Vitro Pharmacokinetic Assays

In Vivo Pharmacokinetic Assays

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Micromolecular Drugs Bioanalysis

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01 One-stop Integrated Services

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02 Innovative Drug Services

Nucleic Acid Drug R&D Platform

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PROTAC Drug Discovery Research Platform

ADC R&D Service Platform

03 Key Technical Services for Drug R&D

Green Chemistry Platform

Process Department Solid Form Screening Platform

SEND Format Conversion Platform

Flow Cytometry Technology Platform

Safety Assessment Lab of Process Chemistry

Drug Forming Research Platform

Metabolite Identification (MetID) Service Platform

Cytokine and Biomarker Detection Platform

04 Drug Efficacy Evaluation for Common Diseases

Rodent Cerebrovascular Disease Drug Efficacy Evaluation System

Pharmacodynamic Evaluation Model Platform for Inflammatory and Immune Diseases

IO Pharmacodynamic Model Evaluation Platform

05 Advanced Preparation R&D

Skin Topical Preparation R&D

Ophthalmic drug R&D platform

Inhalation drug R&D platform

06 Drug Analysis

07 Public Services

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Xenograft Models

We can provide various xenograft models to test the effectiveness of drugs according to our clients' requirements. Typical diseases include head and neck cancer, lung cancer, breast cancer, gastric cancer and pancreatic cancer, with mice, rats and hamsters as test subjects. We are committed to providing clients with mature orthotopic models for evaluating the in vivo efficacy of ADC, completing the modeling and feeding of model animals in an AAALAC-accredited environment, and relevant pharmacodynamic evaluation experiments standards of a GLP level.

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Xenograft Models

Cancer Type	Cell Line
Breast cancer	BT-474,HCC1569,HCC1954,HCC70,JIMT-1,MCF-7,MDA-MB-231,MDA-MB-468,MX-1,SUM149PT,ZR-75-1,HCC1806,SUM159,Bcap-37, 2LMP,ZR-75-30, MDAMB-361
Colon cancer	COLO 205,DLD-1,HCT 116,HCT-15,HT-29,LIM-1215,LOVO,LS 174T,NCI-H508,RKO,SW480,SW620,COLO 201, COLO 320 DM, CW-2,HCT-8,LS1034, LS411N, NCI-H716,SW48
Endometrium	AN3 CA,HEC-1-A, ME-180, MFE-280
Gastric	Hs746T,NCI-N87,SNU-16,MKN45, BGC-823, HGC-27, MKN-28, NUGC-3, SCH, SGC-7901
Glioblastoma	U-87MG,U-87 MG-Red-Fluc(PE),LN-229
Thyroid gland medullary	TT
Hepatocellular	Hep G2,HuH-7,Bel-7402, Hep-3B, PLC/PRF/5, QGY-7703, SK-HEP-1, SMMC-7721
Leukemia	CCRF-CEM,HEL,HL-60,K-562,MV-4-11,THP-1,Karpas-299,MOLT-4,MOLM13
Lung	A-549,Calu-1,Calu-3,Calu-6,HCC827,MSTO-211H,NCI-H1299,NCI-H1650,NCI-H1975,NCI-H2122,NCI-H2228,NCI-H292,NCI-H358,NCI-H460,NCI-H520,NCI-H526,NCI-H69,NCI-H727,PC-9,NCI-H1581,NCI-H3122,DMS114, NCl-H146, NCl-H209, NCI-H446,NCI-H1688,95-D, NCI-H226
Lymphoma	SU-DHL-4,DB,SU-DHL-6,Mino,Daudi,Jeko-1,Raji,TMD-8,WSU DLCL2,DOHH2,OCI-LY19,OCI-LY10,MM.1S,RPMI-8226,OPM2
Melanoma	A375, A2058, C32, HMCB, SK-MEL-30, MDA-MB-435s, WM-226-4
Myeloma	MM.1S,NCI-H929,RPMI-8226,OPM-2,KMS-11, KMS-26
Neuroblastoma	SH-SY5Y
Ovary	A2780,OVCAR-3,SK-OV-3,ES-2, HO-8910PM, PA-1
Pancreatic	AsPC-1,Bx PC-3,Capan-1,Capan-2,CFPAC-1,HPAF-II ,MIA PaCa-2,PANC-1,SU.86.86
Pharynx	FaDu, Detroit 562, CAL-27
Prostate	DU 145,PC-3, LNCap, CL-1
Renal	786-O,OS-RC-2,A498,ACHN
Skin	A-431, Colo829
Urinary Bladder	RT4
Oral Epithelial Carcinoma	KB
Urinary Bladder Cancer	HT-1197, HT-1376, RT4, SCaBER, SW780, T24
Cervical Cancer	SiHa, Hela
Osteosarcoma	MG-63, SJSA-1
Fibrosarcoma	HT-1080
Muscle, Striated	SJCRH30

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Xenograft Models Orthotopic Cancer Models Syngeneic Mouse Models Humanized Mouse Models GEM Models PDX Models