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Preclinical research
Xenograft Models
We can provide various xenograft models to test the effectiveness of drugs according to our clients’ requirements. Typical orthotopic diseases include head and neck cancer, lung cancer, breast cancer, gastric cancer and pancreatic cancer, with mice, rats and hamsters as test subjects. We are committed to providing clients with mature orthotopic models for evaluating the in vivo efficacy of ADC, completing the modeling and feeding of model animals in an AAALAC-accredited environment, and relevant pharmacodynamic evaluation experiments standards of a GLP level.
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Xenograft Models
Cancer TypeCell Line
Breast cancerBT-474,HCC1569,HCC1954,HCC70,JIMT-1,MCF-7,MDA-MB-231,MDA-MB-468,MX-1,SUM149PT,ZR-75-1,HCC1806
Colon cancerCOLO 205,DLD-1,HCT 116,HCT-15,HT-29,LIM-1215,LOVO,LS 174T,NCI-H508,RKO,SW480,SW620
EndometriumAN3 CA,HEC-1-A
GastricHs746T,NCI-N87,SNU-16,MKN45
GlioblastomaU-87MG,U-87 MG-Red-Fluc(PE),LN-229
Thyroid gland medullaryTT
HepatocellularHep G2,HuH-7
LeukemiaCCRF-CEM,HEL,HL-60,K-562,MV-4-11,THP-1,Karpas-299,MOLT-4,MOLM13
LungA-549,Calu-1,Calu-3,Calu-6,HCC827,MSTO-211H,NCI-H1299,NCI-H1650,NCI-H1975,NCI-H2122,NCI-H2228,NCI-H292,NCI-H358,NCI-H460,NCI-H520,NCI-H526,NCI-H69,NCI-H727,PC-9,NCI-H1581,NCI-H3122
LymphomaSU-DHL-4,DB,SU-DHL-6,Mino,Daudi,Jeko-1,Raji,TMD-8,WSU DLCL2,DOHH2,OCI-LY19,OCI-LY10,MM.1S,RPMI-8226,OPM2
MelanomaA-375
MyelomaMM.1S,NCI-H929,RPMI-8226,OPM-2
NeuroblastomaSH-SY5Y
OvaryA2780,OVCAR-3,SK-OV-3
PancreaticAsPC-1,Bx PC-3,Capan-1,Capan-2,CFPAC-1,HPAF-II ,MIA PaCa-2,PANC-1,SU.86.86
PharynxFaDu
ProstateDU 145,PC-3
Renal786-O,OS-RC-2,A498
SkinA-431
Urinary BladderRT4
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