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Carbohydrate Chemistry

Carbohydrate Chemistry

All organisms are composed of four types of biological macromolecules: carbohydrates, lipids, nucleic acids, and proteins, as well as water and inorganic ions. Carbohydrates are the most widely distributed type of biomolecules in nature and the third type of biological macromolecules with important biological significance in addition to proteins and nucleic acids. Carbohydrates serve as the source of energy and the center of material circulation, as well as an important skeleton and support unit for maintaining cell morphology and structure.
Carbohydrate synthesis
  • Carbohydrates are important organic compounds with diverse biological activities and applications. They play an important role in biological growth and development, immune response, signal transduction and other life processes. Carbohydrate compounds and modifications can not only be used as drugs, but also act as important targeted drug delivery systems. Carbohydrate compounds include monosaccharides, oligosaccharides, polysaccharides, glycoconjugates (glycolipids, glycopeptides and glycoproteins), etc.
    The sources of carbohydrate compounds include carbohydrate drugs of natural origin and carbohydrate drugs of synthetic origin. Natural sources of carbohydrates mainly include polysaccharides from microorganisms such as plants and fungi; synthetically derived carbohydrate drugs are chemically modified on the natural carbohydrate structure, semi-synthetic carbohydrate drugs, fully synthetic glycosides, oligosaccharides and glycoconjugates compound drugs. Enzymatic chemical synthesis plays an increasingly important role in the synthesis of carbohydrate compounds.
Sugar modifications
  • Medicilon can complete the chemical synthesis and modification of nucleic acid drugs, including ribose modification, base modification, backbone modification, and delivery system modification.

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Laboratory equipment
  • Medicilon is equipped with advanced instruments, including NMR (Nuclear Magnetic Resonance), HPLC (High-Performance Liquid Chromatography), SFC (Supercritical Fluid Chromatography), MS directional preparative HPLC, microwave reactor, DSC (Differential Scanning Calorimetry), TGA(Thermogravimetry Analysis), ICP-MS((Inductively coupled plasma-mass spectrometry), etc.
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