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Drug Discovery
Chemistry Research

Chemistry Research

Medicilon's chemistry department consists of synthetic chemistry services and medicinal chemistry services. Clients can work with us on a Fee for Service or Full Time Equivalent basis.

In 2021, Medicilon established the International Discovery Service Unit (IDSU). The IDSU provides global pharmaceutical companies with high quality, efficient and cost-effective chemistry synthesis design and production and medicinal chemistry. The IDSU supports the discovery and delivery of clinical candidate compounds forglobal drug research and development.

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  • Medicilon Photochemistry Platform
    Medicilon has been developing new technologies over the years, integrating emerging methods of green chemistry into its services, using currently popular photoredox chemistry, electrochemisty, catalyst screening, continuous reactions, etc., to provide our customers with high-quality economic solutions.
    Highly experienced in different types of photochemistry reactions Full capacity for the synthesis of a variety of catalysts for photocatalytic reactions Strong expertise in photoredox chemistry
Service Models
At Medicilon, we offer a full range of chemical services covering all phases of your project. Cus-tomers can work with us either through FFS or FTE.
  • Full Time Equivalent(FTE)
    Team composition: fixed team, with team leaderAnalytical and logistic support included
  • Fee For Service (FFS)
    Clearly stated labor cost, material cost, and project timeline
Technology Platform
  • Photochemistry platform   Metal catalysts screening platform   Electrochemical platform   Photoredox reaction
Drug R&D Service Platform
  • Medicilon has 50+Payloads,200+Linkers,30+Payloads+Linkers. Up until the end of 2022, Medicilon undertook more than 100 major IND application biopharmaceutical projects, including monoclonal antibodies, bispecific antibodies, polyclonal antibodies, ADCs, viral vaccines and fusion proteins. As of May 8, 2023, Medicilon has successfully assisted 17 ADC drugs to obtain clinical approval, and more than 10 ADC projects are in development.
  • Medicilon has access to many of the popular POI ligands and multiple tissue types of E3 ligase ligands, in addition to having established a linker library containing hundreds of diverse molecules.As of the end of June 2023, Medicilon has successfully assisted 5 PROTAC drugs to abtain clinical approval, and more than 20 PROTAC projects are under development.
  • The Medicilon nucleotide drug R&D platform can provide a one-stop option for monomer synthesis and modification; oligonucleotide synthesis; delivery system synthesis and oligonucleotide conjugate synthesis. The siRNA library that has been built has a rich monomer inventory anda large monomer synthesis building block library, to support the synthesis of various modified monomers.
Service Cases

pan-FGFR1-4 irreversible inhibitor RG002 tablets was approved for clinical use.webp

Pan-FGFR1-4 irreversible inhibitor RG002 tablets was approved for clinical use

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SHP2 allosteric inhibitor RG001 tablet to be approved for clinical use.webp

Anti-tumor class I new drug SHP2 allosteric inhibitor RG001 tablet has been approved for clinical use

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ABM Therapeutics presented Medicilon with a commemorative trophy of our first candidate compound.webp

ABM Therapeutics presented Medicilon with a commemorative trophy of "our first candidate compound"

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For more service cases, please contact us:

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Laboratory Instruments
  • The Chemistry department has more than 20,000 square meters of laboratory space and is equipped with advanced laboratory and analytical instruments:
    NMRHPLCSFCUPLC-MSLC/MSDSCTGAICP-MS
    The setup of our lab ensures that chemists can access all equipment and devices whenever needed.
Learn more about "Chemistry Research"
Relevant laboratoriesRelevant laboratories
  • NMR
  • High activity laboratory
  • Overnight synthesis laboratory
  • Overnight synthesis laboratory
  • Overnight synthesis laboratory
  • microwave
  • ICP-MS
  • HPLC
  • Chemistry's lab
  • SFC
  • NMR
  • TGA
  • GC-MS
  • Overnight synthesis laboratory
  • Overnight synthesis laboratory
  • Overnight synthesis laboratory
  • High activity laboratory
Relevant articlesRelevant articles