Humanized Mouse Models

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Model Type

• PBMC Humanized Models
  The humanized mouse model of local human immune system is particularly effective for short-term research or high-throughput research.
  Currently, we have the following model types available:

  Cancer Type	Cell Lines
  Brain Cancer	U-87 MG
  Breast Cancer	HCC1954, MDA-MB-231, JIMT-1
  Colon Cancer	HT29, LoVo, Ls174T
  Gastric Cancer	NCI-N87
  Leukemia	THP-1
  Lung Cancer	HCC827, NCI-H1975, NCI-H292, A549
  Lymphoma	Raji, TMD8, MOLM-13
  Melanoma	A375
  Myeloma	RPMI-8226, NCI-H929, MM.1S
  Ovarian Cancer	OVCAR-3
  Pancreatic Cancer	Capan-2
  Renal Cancer	786-O
  Skin Cancer	A431
  Bladder cancer	UM-UC-3
  Prostate	PC-3
  Pharynx	FaDu
  Liver	Hep G2
  Thyroid / medulla	TT
  Uterus; endometrium	Ishikawa

  
• CD34+ HSC Humanized Models
  The CD34+ HSC humanized models with transplanted human umbilical cord blood cells-reconstructed hemopoietic system is implanted in the bone marrow of mice, and can produce various kinds of humanized hematopoietic cells and immune cells constantly and stably. All kinds of immunotherapy will be evaluated by the human immune system.
  Currently, we have the following model types available:

  Cancer Type	Cell Lines
  Breast cancer	HCC1954
  Colon cancer	HT29, Lovo, Ls174T
  Lung cancer	NCI-H292, HCC827
  Leukemia	THP-1
  Lymphoma	Raji, MOLM-13
  Myeloma	NCI-H929
  Skin cancer	A431
  Ovarian Cancer	OVCAR-3

  

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