Inflammatory & Immune Diseases Models

At present, as the pathogenesis of inflammatory and immunological diseases is unclear, there are few effective therapeutic drugs available in clinical practice. In such a context, the appropriate preclinical research techniques and models are required to help companies and researchers further develop and evaluate new drugs. Our Preclinical Pharmacodynamics Department has been deeply involved in this field for years, developing reliable animal-based efficacy evaluation models aimed at different targets and pathways, thus facilitating the clinical transformation of new drugs.

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Diseases	Inflammatory and Immunological Disease Models	Animals
Arthritis	Chronic infectious arthritis (CIA)	Mice/rats
	Adjuvant induced-arthritis (AIA)	Rats
	Pristane-induced arthritis (PIA)	Rats
	Carrageenan-induced arthritis	Rats
	Experimental allergic encephalomyelitis (EAE)	Mice
Psoriasis	Estrogen-induced vaginal epithelium mitosis	Mice
	Tail scales	Mice
	IL-23-induced auricle epidermal dysplasia	Mice
	Imiquimod-induced	Mice
	Propranolol-induced	Guinea pigs
Atopic dermatitis and eczema	Dinitrofluorobenzene (DNFB)-induced	Mice
	Dinitrochlorbenzene + OX-induced	Mice
	Phorbol ester-induced	Mice
Acute inflammation	Toe swelling	Rats/mice
	Auricle swelling	Mice
	Capillary permeability test	Rats/mice
	Granuloma proliferation	Rats

FAQ

What are the Most Common Autoimmune Diseases?

Autoimmune diseases are a series of diseases caused by autologous tissue damage caused by the body's immune response to self-antigens, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), psoriasis, and atopic dermatitis.

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