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Inflammatory & Immune Diseases Models

Inflammatory & Immune Diseases Models

As the pathogenesis of inflammatory and immunological diseases is unclear, there are few effective therapeutic drugs available in clinical practice. In this context, the appropriate preclinical research techniques and models are required to help companies and researchers further develop and evaluate new drugs. Our Preclinical Pharmacodynamics Department has been involved in this field for years, developing reliable animal-based efficacy evaluation models aimed at different targets and pathways, thus facilitating the clinical transformation of new drugs.
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DiseaseTypeSpecies
ArthritisAcute joint inflammation induced by carrageenanRat
Acute joint inflammation induced  CFAMouse/Rat
Rheumatoid arthritis induced by II Collagen (CIA model)Mouse/Rat
Rheumatoid arthritis induced by Complete Freund’s Adjuvant  (AIA model)Rat
Gouty arthritis model induced by sodium urateRat
OsteoarthritisSodium iodoacetate (MIA) induced osteoarthritisRat
Partial Medial Meniscectomy (pMMx) induced osteoarthritisRat
Partial Medial Meniscectomy with Anterior Cruciate Ligament  severed (pMMx + ACLT) osteoarthritisRat
OsteoporosisOsteoporosis model of castrated female ratRat
Osteoporosis model induced by retinoic acid ARat
Glucocorticoid-induced osteoporosis modelRat
PsoriasisEstrogen  induced vaginal epithelium mitosisMouse
Tail scale modelMouse
IL-23 induced auricle epidermal dysplasiaMouse
Back skin psoriasis induced by imiquimodMouse
Atopic dermatitis and eczemaChronic atopic dermatitis model induced by DNFBMouse/Rat
Subacute eczema-like model induced by DNFBMouse
Phorbol ester induced eczema modelMouse
Multiple sclerosis , Amyotrophic lateral sclerosis (MS,ALS)EAE allergic encephalomyelitis model (EAE)Mouse
Cuprizone-induced demyelination of brain tissueMouse
Acute inflammationAuricle swelling modelMouse
Toe swelling modelRat
Capillary permeability testMouse/Rat
Granuloma proliferation modelRat
Inflammatory and Immune Diseases Platform
FAQ
  • What are the Most Common Autoimmune Diseases?

    Autoimmune diseases are a series of diseases caused by autologous tissue damage caused by the body's immune response to self-antigens, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), psoriasis, and atopic dermatitis.

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