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Preclinical Research

Inflammatory & Immune Diseases Models

At present, as the pathogenesis of inflammatory and immunological diseases is unclear, there are few effective therapeutic drugs available in clinical practice. In such a context, the appropriate preclinical research techniques and models are required to help companies and researchers further develop and evaluate new drugs. Our Preclinical Pharmacodynamics Department has been deeply involved in this field for years, developing reliable animal-based efficacy evaluation models aimed at different targets and pathways, thus facilitating the clinical transformation of new drugs.
DiseasesInflammatory and Immunological Disease ModelsAnimals
ArthritisChronic infectious arthritis (CIA)Mice/rats
Adjuvant induced-arthritis (AIA)Rats
Pristane-induced arthritis (PIA)Rats
Carrageenan-induced arthritisRats
Experimental allergic encephalomyelitis (EAE)Mice
PsoriasisEstrogen-induced vaginal epithelium mitosisMice
Tail scalesMice
IL-23-induced auricle epidermal dysplasiaMice
Propranolol-inducedGuinea pigs
Atopic dermatitis and eczemaDinitrofluorobenzene (DNFB)-inducedMice
Dinitrochlorbenzene + OX-inducedMice
Phorbol ester-inducedMice
Acute inflammationToe swellingRats/mice
Auricle swellingMice
Capillary permeability testRats/mice
Granuloma proliferationRats
  • What are the Most Common Autoimmune Diseases?

    Autoimmune diseases are a series of diseases caused by autologous tissue damage caused by the body's immune response to self-antigens, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), psoriasis, and atopic dermatitis.

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