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Inflammatory & Immune Diseases Models

Inflammatory & Immune Diseases Models

As the pathogenesis of inflammatory and immunological diseases is unclear, there are few effective therapeutic drugs available in clinical practice. In this context, the appropriate preclinical research techniques and models are required to help companies and researchers further develop and evaluate new drugs. Our Preclinical Pharmacodynamics Department has been involved in this field for years, developing reliable animal-based efficacy evaluation models aimed at different targets and pathways, thus facilitating the clinical transformation of new drugs.
ArthritisAcute joint inflammation model in rats caused by carrageenan gumRat
CIA-induced ankylosis modelMouse/Rat
CFA-induced gout-like arthritis (AIA) modelRat
Sodium urate-induced gouty arthritis modelRat
Hypocretin-induced arthritis model in rats (PIA)Rat
Osteoarthritis modelSodium iodoacetate (MIA)-induced osteoarthritis modelRat
pMMx-induced osteoarthritis modelRat
pMMx+ACLT-induced osteoarthritis modelRat
Osteoporosis modelOsteoporosis model in desiccated female ratsRat
Glucocorticoid-induced osteoporosis modelRat
Retinoic acid A-induced osteoporosis modelRat
PsoriasisMouse vaginal epithelial mitosis modelMouse
Mouse tail scales modelMouse
IL-23 induced aberrant epidermal hyperplasia model in mouse auricleMouse
Imiquimod-induced psoriasis-like model in miceMouse
Atopic Dermatitis (AD)DNFB-induced chronic atopic dermatitis modelMouse
DNCB+OX-induced chronic atopic dermatitis modelMouse
DNFB-induced subacute eczema-like modelMouse
Fluport-induced acute eczema-like modelMouse
Multiple sclerosis model (MS, ALS)EAE experimental allergic encephalomyelitis mouse modelMouse
Cuprizone-induced demyelination model of mouse brain tissueMouse
Inflammatory swelling modelMouse auricular swelling model Mouse
Rat toe swelling modelRat
Capillary permeability assayMouse/Rat
Carbon contouring assayMouse
Yeast-induced fever modelMouse
Passive skin allergic reaction (PCA)Mouse/Rat
Inflammatory and Immune Diseases Platform
  • What are the Most Common Autoimmune Diseases?

    Autoimmune diseases are a series of diseases caused by autologous tissue damage caused by the body's immune response to self-antigens, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), psoriasis, and atopic dermatitis.

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