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| Disease | Type | Species |
|---|---|---|
| Depression | Forced swimming test | Mouse/Rat |
| Tail suspension test | Mouse | |
| 5-HTP-induced head twitches response | Mouse | |
| Reserpine-induced ptosis | Mouse | |
| Yohimbine-induced lethality test | Mouse | |
| High-dose apomorphine antagonism | Mouse | |
| Chronic unpredictable mild stress (CUMS) | Rat | |
| Novelty suppressed feeding test | Mouse/Rat | |
| MAO-A/MAO-B activity test | Mouse/Rat |
| Disease | Type | Species |
|---|---|---|
| Convulsant | Pentylenetetrazol-induced clonic seizure | Mouse |
| Bicuculline-induced clonic seizure | Mouse | |
| Yohimbine-induced lethality test | Mouse | |
| Picrotoxin-induced clonic seizure | Mouse | |
| Sedative hypnosis anti-anxiety | Synergistic effect with pentobarbital | Mouse |
| Synergies with pentobarbital drugs | Mouse | |
| Wake up and fall asleep again | Mouse | |
| Open field test (video monitoring, software processing) | Mouse/Rat | |
| Elevated plus maze test (video monitoring, software processing) | Mouse/Rat | |
| Shuttle Box test (video monitoring, software processing) | Mouse | |
| Schizophrenia | MK801 induced schizophrenia (positive/negative symptom) | Mouse |
| Ketamine induced schizophrenia with negative symptom | Mouse | |
| Haloperidol-induced catalepsy | Rat | |
| Lower lip retraction test | Rat | |
| Apomorphine-induced rotation test | Mouse | |
| Hyperactivity induced by amphetamine | Rat | |
| Hyperactivity induced by phencyclidine | Rat | |
| Parkinson’s Disease | Subacute model induced by MPTP | Mouse |
| Chronic model (MPTP + probenecid induction) | Mouse | |
| Oxotremorine-induced tremors/salivation | Mouse |
| Disease | Type | Species |
|---|---|---|
| Nociceptive Pain | Hot- or cold-plate tests, Radiant heat tail-flick test, Randall-Selitto test | Mouse/Rat |
| Von-Frey filaments test | Mouse/Rat | |
| Acetic acid writhing test | Mouse | |
| Formalin model (phase I & phase II) | Mouse | |
| Model of foot inflammatory pain model induced by Complete Freund’s Adjuvant (CFA) | Mouse/Rat | |
| Model of foot inflammatory pain (Carrageenan induction) | Mouse/Rat | |
| L5/L6 spinal nerve ligation (SNL) | Rat | |
| LPS-induced thermal hyperalgesia | Mouse/Rat | |
| Sciatic nerve injury (SNI) model | Mouse/Rat | |
| Incision-induced pain model | Rat | |
| Diabetic foot ulcer pain model | Mouse/Rat | |
| Chemotherapy pain model (Vincristine induction) | Rat | |
| Chemotherapy pain model (Paclitaxel induction) | Rat | |
| Osteoarthritis pain model (pMMx + ACLT induction) | Rat | |
| Osteoarthritis pain model (MIA induction) | Rat |
| Disease | Type | Species |
|---|---|---|
| Dementia | Memory acquisition impairment | Mouse/Rat |
| Memory consolidating impairment | Mouse | |
| Memory retrieval impairment | Mouse | |
| Light-dark box test | Mouse | |
| Morris water maze test | Mouse/Rat | |
| Activity of acetylcholinesterase test | Mouse/Rat | |
| D-galactose-induced subacute aging model | Mouse | |
| Novel object recognition (NOR) test | Rat | |
| APP/PS1/Tau transgenic mice (Morris water maze, CognitionWall) | Transgenic Mouse |
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