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Orthotopic Cancer Models

Orthotopic Cancer Models

The orthotopic cancer model assesses the interaction between tumor cells and drugs in their natural organ/microenvironment and monitors tumor growth in situ. We have a variety of mature orthotopic transplantation models available, including brain, liver, lung, tibial bone marrow cavity, and intravesical orthotopic transplantation models.
Medicilon icon-diamond.pngModel Type
Cancer TypeOrthotopic ModelsOrthotopic Models (Luc Cell Line)
Lung cancerNCI-H1650, A549, NCI-H1975, NCI-H460 and LLC1A549-luc, LLC1-luc and NCI-H1975-luc
Colon cancerHCT-116 and LoVoHT29-luc,CT26.WT-luc
Gastric cancerHs 746T
Pancreatic cancerMia-Paca 2Mia-Paca 2-luc
Breast cancerMDA-MB-231,HCC1954, HCC70,MDA-MB-361, MCF7, HCC19544T1-luc,MDA-MB-231-luc
Ovary carcinomaSK-OV-3SK-OV-3-luc
Prostate cancerPC3PC-3-luc
Kidney cancerA498
Bladder cancerUM-UC-3
Liver cancerH22
LeukemiaRL, MAVER-1, Karpas299, K562,HL-60
Medicilon icon-diamond.pngMature Orthotopic Technique
  • Orthotopic brain tumor models
    Orthotopic brain tumor models.png
  • Lung tumor models
    Lung tumor models.png
    Tibia marrow cavity tumor models
    Tibia marrow cavity tumor models.png
  • Ovary carcinoma models
    Ovary carcinoma models.png
Relevant laboratories
  • caliper
  • BD-FACSCelesta
  • BD-LSRFortessa
  • IVIS-Lumina-III-In-Vivo-Imaging-System
  • RAD
  • frozen section
  • Pathological observation
  • pathological section
  • Operating room (outer room)
  • flow cytometer
Relevant articles