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Jan 04,2022
Sincere Collaboration, New and Far-Reaching - Bao Pharmaceutical and Medicilon reached a strategic collaboration
On December 17, 2021, Shanghai Bao Pharmaceutical Co., Ltd. (Bao) and Shanghai Medicilon Inc. (Medicilon) signed an innovative drug IND R&D service strategy collaboration agreement.
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Oct 25,2021
Medicilon Symposium – “Preclinical Development Strategy of Innovative Drugs Driven by Translational Medicine” was Successfully Held
The 4th Annual Precision Medicine and Immuno-Oncology China Summit 2021 (PMIO China 2021) was successfully held in Zhangjiang, Shanghai recently.  Shanghai Medicilon Inc. (Medicilon) and
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Jan 11,2022
Medicilon Assisted DAC Biotechnology's Fourth ADC Drug DXC007 Getting Approved for Clinical Use
On December 28, 2021, Hangzhou DAC Biotechnology Co., Ltd. (DAC Biotech) DXC007 project was successfully approved for clinical trials. DXC007 is the fourth ADC drug approved for clinical use by DAC Biotech, and it is also the fourth ADC drug that Shanghai Medicilon Inc. (Medicilon) to help DAC Biotech successfully getting approval.
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Jan 11,2022
Medicilon Assisted Regor Therapeutics Group's New-generation Tumor-targeting Inhibitor RGT-419B Getting Approved for Clinical Use
On December 28, 2021, the new generation of CDK2/4/6 small molecule inhibitor RGT-419B independently developed by Regor Therapeutics Group (Regor) was approved by the U.S. Food and Drug Administration (FDA).
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Jan 07,2022
Join Medicilon at Precision in Drug Discovery & Preclinical 2022 Summit

DATE: Sep 28-29, 2022

LOCATION: Frankfurt, Germany (Europe)

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Jan 04,2022
Recording the Growth of Medicilon in 2021
This year, Medicilon, with persistent belief, courageously and innovatively, pursued quality, and gave birth to the power of joint growth. Today, we take you to review the 2021 and witness the growth and progress of Medicilon!
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Oct 18,2021
The Internationalization Trend of Chinese Pharmaceutical Companies and AI R&D Innovation Forum
Two forum themes, an inaugural meeting of Zhangjiang AI New Drug R&D Alliance Establishment, three keynote speeches, three rounds of roundtable discussion, a gathering of
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Jan 19,2022
Medicilon MPTP Parkinson Disease Model
Medicilon has effective models for evaluating new drugs for Parkinson, including MPTP-induced mouse subacute PD model, MPTP+ probenecid-induced mouse chronic PD model, oxytremorine-induced cholinergic symptom model, etc.
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Jan 17,2022
What is ADME?
What is ADME? ADME means absorption, distribution, metabolism and excretion of drugs in organisms.
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Jan 07,2022
DRUG DISCOVERY 2021: RECONNECT WITH MEDICILON

DATE: 19-20 Oct, 2021

LOCATION: The exhibition center, ACC, Liverpool

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Dec 29,2021
Drug Discovery
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Nov 19,2021
Discovery and Optimization of Lead Compounds
Discovery of Lead Compounds Hit to Lead The discovery of lead compounds is the process of turning the “hits” found in screening into “lead compounds” that can be further optimized. The lead compound may be a selected compound or a series of homologs, or it may be a compound derived from literature. However, for high-throughputRead more
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Nov 19,2021
Injection vs. Oral Solid Dosage
From the perspective of various stages, there are big differences between domestic generic drug injections and oral solid dosages in terms of generic drug consistency evaluation, competition pattern, and overall market size. Domestic sales of injections account for too much From the PDB sample data, injections account for more than 60% of domestic prescription drugRead more
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Nov 18,2021
Consistency Evaluation of Oral Solid Dosage
As of May 2019, starting from the formal acceptance of the first conformity evaluation product in 2017, there have been nearly 900 oral solid dosage forms for conformity evaluation. The dosage forms include tablets, capsules, powders, sustained-release capsules, etc. At present, more than 200 product specifications have passed the consistency evaluation. The consistency evaluation ofRead more
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Nov 16,2021
Liver Microsome Model of Drug Metabolism Model in Vitro
For those drugs with low metabolic rate, high toxicity, or lack of sensitive detection methods, in vitro drug metabolism studies can eliminate the interference of internal factors and provide reliable theoretical data for the overall experiment. The liver microsomal model is one of the common in vitro models for studying drug metabolism in laboratories. ItRead more
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Nov 16,2021
Basic Parameters and Abbreviations in Pharmacokinetic Tests
Pharmacokinetic Parameters Pharmacokinetic parameters represent the parameters of the mathematical model of the process of drug absorption, distribution, excretion and structural transformation in the body. Absorption Dissolution: the degree to which the drug molecule is dissolved in the digestive tract Bioavailability: the degree of drug absorption Absolute bioavailability Maximum blood concentration (Cmax) Peak time (Tmax)Read more
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Nov 16,2021
Pre-clinical Research Escorts the Development of Innovative Drugs
The first challenge in drug development is the pre-clinical research of new drugs, which refers to the chemical synthesis or natural product purification research, drug analysis research, pharmacodynamics, pharmacokinetics, and toxicology that are carried out before the drug enters clinical research. And pharmaceutics research. Preclinical research on new drugs escorts the development of innovative drugs.Read more
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Nov 12,2021
Non-labeled Natural Product Target Identification and Validation
The structure of natural products is complex and rich, with a wide range of biological activities, and is an important source of new drug innovation. According to statistics, nearly half of the drugs approved by the U.S. Food and Drug Administration (FDA) for cancer treatment in the past 30 years Medicines are directly or indirectlyRead more
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Nov 12,2021
Artificial Intelligence Helps Drug Development
On October 22, 2021, the research group of Academician Hualiang Jiang and Mingyue Zheng from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences published an article Drug target inference by mining transcriptional data using a novel graph convolutional network framework on Protein & Cell. Researchers applied the Twin Spectrogram Convolutional Network (SSGCN) toRead more
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Nov 12,2021
Target Validation and Drug Discovery
Since the completion of the Human Genome Project in 2003, researchers have been trying to find molecular targets related to specific phenotypes. Many experimental techniques have been developed for the confirmation of new disease targets and the discovery of lead compounds. In addition, the increase in the number of protein structures and the increase inRead more
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