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On April 8, 2021, the clinical trial application of HG381 for injection, developed by HitGen, was approved by National Medical Products Administration (NMPA).  HG381 for injection is a new Category I Chemical Drug and is clinically intended to be used for the treatment of advanced tumors. HG381 is new molecular entity developed by HitGen basedRead more

In the past ten years, the cycle of drug discovery and development has become longer and longer, and the cost of testing has increased. In Western countries, it takes 10 to 15 years to develop and market a new compound entity, and it costs more than US$800 million. Of the 10,000 new compound entities, 10Read more

Zhangjiang Runhe International Office Garden Opened On April 15, 2020, the opening ceremony of Zhangjiang Runhe International Office Garden was successfully held.  The Member of the Standing Committee and Deputy Mayor of Shanghai Municipal Committee, Qing Wu, led several of the Shanghai government officials and business representatives attended the ceremony. Zhangjiang Runhe International Office GardenRead more

On April 10th 2020, the Deputy Mayor of Shenzhen Municipal Government Nie Xinping and his team visited Medicilon for the research.  Dr. Chunlin Chen, Founder & CEO of Medicilon, accompanied the research and report. During the visiting for the research, Dr. Chen introduced the 16 years of development history of Medicilon, a one-stop preclinical newRead more

In 2019, Medicilon has had an extraordinary year. The steadily developing Medicilon made a huge accumulation in 2019 and achieved a qualitative leap.  Let us look back on the moments of glory and Extraordinary “2 0 1 9”. 2 – Double Happiness I Listed on Sci-Tech Innovation Board in Shanghai On Nov. 5th 2019, ShanghaiRead more

  Application Background One of the most important steps in developing a new drug is target identification and validation.  Target-based drug discovery has become the prevailing paradigm used by pharmaceutical and biotechnology companies. This approach is appealing because it holds the promise of identifying more efficacious compounds with fewer undesirable side effects. Good target identificationRead more

Preclinical Drug Development Process Drug development is time consuming and costly which contains preclinical, clinical and after-market. In principle, if all the processes are straight-forward, a drug can be developed in a seven year period. In practice, drug development takes in excess of twelve years. Procedures are tightly regulated both for safety and to ensureRead more

Medicilon’s medicinal chemistry involves the application of a number of specialized disciplinary approaches all focused on the ultimate goal of drug discovery.  Drug target identification and validation, rational (target-based) drug design, structural biology, computational-based drug design, methods development (chemical, biochemical and computational), and “Hit-to-lead” development are all aspects of medicinal chemistry.  The techniques and approachesRead more