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Home Search results for "Ligand Binding Assay"

Different Bioanalysis platforms

By medicilon | Featured Stories | Comments are Closed | 2 December, 2020 |

Bioanalysis is an important part of the drug development process, including pharmacokinetics (PK) and biomarker analysis, which runs through the entire process of drug development from early screening to clinical research to post-marketing monitoring. Pharmacokinetics is usually an important end point of clinical research. Non-clinical and clinical pharmacokinetics not only guide the dosage selection ofRead more

Overview of LBA test methods in bioanalysis

By medicilon | Featured Stories | Comments are Closed | 2 December, 2020 |

The biological analysis described in this article is to determine the concentration of biological drugs in animal and human body fluids or tissues (this article specifically refers to protein biological drugs, including monoclonal antibodies, cytokines, auxins, fusion proteins, etc.). Most bioanalytical methods are based on immunoassays (Immunoassays), or more broadly called, ligand binding assays (LBA).Read more

Ligand Binding Test Biological Analysis

By medicilon | Featured Stories | Comments are Closed | 2 December, 2020 |

In the previous issues, I shared the past and present of the matrix effect of small molecule LC-MS/MS bioanalysis with friends in the circle. This issue returns to the topic of macromolecular bioanalysis. Ligand Binding Assay (LBA) is the most widely used detection method for macromolecular bioanalysis. LBA is based on the equilibrium reaction betweenRead more

Ligand Binding Assay

By medicilon | Featured Stories | 0 comment | 6 June, 2017 |

There are numerous types of ligand binding assays, both radioactive and non-radioactive.  As such, ligand binding assays are a superset of radio-binding assays, which are the conceptual inverse of radioimmunoassays (RIA). Some newer types are called “mix-and-measure” assays because they do not require separation of bound ligands. Ligand binding assays are used primarily in pharmacologyRead more

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  • Home
  • About
    • Medicilon Overview
    • Executive Team
    • CEO Message
    • Corporate Culture
    • Company History
    • Honor
  • Services
    • Integrated Projects
      • Antibody-Drug-Antibody (ADC)
      • Preclinical Research Services
      • IND Filing
      • Bio Drug Development
      • Chemical Drug Development
      • Chemical Compound Druggability Assessment
      • Molecular Imaging & Radiochemistry
      • OINDP Development
      • Preclinical Ophthalmic Research Platform
    • Pharmacology Services
      • Cancer Xenograft Models
      • Orthotopic Models
      • Syngeneic Mouse Models
      • Transgenic Mouse Model
      • Humanized Mouse Model (hPBMCEngrafted)
      • PDX Model
      • Digestive System Models
      • Neurological Disorders Models
      • Metabolic Disease Models
      • Inflammation & Immunological Disease Models
      • Other Disease Models
    • Chemistry Services
      • Medicinal Chemistry Services
      • Synthetic Chemistry
      • Process Development Services
      • Analytical Chemistry
    • Drug Formulation
      • Pre Formulation Development
      • Analytical Development
      • Formulation Development Services
      • Generics Consistency Evaluation
      • Research on Quality Control
      • Clinical Trial Material
      • OINDP Development
    • Biology Services
      • Discovery Biology Services
      • Recombinant Protein Services
      • Computational Biology & Molecular Modeling
      • Crystallization & Structural Determination
      • Kinase Services
      • SeMet Media Sales
    • Bioanalytical Services
      • Large Molecule Bioanalysis
      • Small Molecule Bioanalysis
    • Pharmacokinetic Services
      • In Vivo Assays
      • In Vitro Assays
    • Drug Safety Evaluation
      • Inhalation Toxicity Assessment
  • Customer
    • Customer Reviews
    • New Models of Collaboration
    • Intellectual Property Protection
    • Download Center
  • Careers
  • News
    • Medicilon Events
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    • Featured Stories
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