Containsynthetic-biologyContent

The preparation and research of APIs is at a critical position in the chemical drug R&D process, and the structure of the prepared compounds is consistent to ensure that subsequent quality control studies, pharmacology and toxicology studies, and clinical studies are meaningful. Through the structure of the synthesized APIs Confirmation can characterize whether the structureRead more

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As an important part of drug research and development, chemically synthesized drugs are still the subject of new drug research and development for major pharmaceutical companies in the world today. The production of chemical drugs is inseparable from three stages: raw material pretreatment, chemical reaction and product refinement. Chemical drugs can be inorganic minerals orRead more

Western blot is a protein detection and analysis technique widely used in the fields of biology and medicine. It can be used to detect the expression level of specific proteins in tissue homogenates or cell extracts. Western blotting technology steps are mainly divided into two parts, namely SDS-polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting. The BiologyRead more

With the rapid development of molecular biology research, especially the human genome project, many new techniques have emerged in order to adapt to the development trend of functional research on many genes or proteins. Yeast two-hybrid is one of them. Yeast two-hybrid is one of them. So let’s briefly understand what is the yeast two-hybridRead more

Molecular biology is the science of studying life phenomena and the essence of life at the molecular level. The molecular biology technology provided by some molecular biology service organizations is a more advanced and cutting-edge technology in life science research. Molecular docking is a key technology in structural molecular biology and has played an increasinglyRead more

Polypeptide is a chemically active substance ubiquitous in organisms. It is a type of compound composed of amino acids connected by peptide bonds. Compared with other chemical drugs and biotechnology drugs, peptide drugs have significant activity, strong specificity, and receptors. The affinity is good, the toxicity is weak, and it is generally not easy toRead more

The preparation and research links of APIs are at a key position in the chemical drug R&D process, and only the same structure of the prepared compounds can ensure that subsequent quality control studies, pharmacological and toxicological studies and clinical studies are meaningful. Through the structure of the synthesized APIs Confirmation can characterize whether theRead more

Cognitive ability refers to the ability of the human brain to process, store and extract information. Although everyone wants to stay sharp forever, the impact of age on cognitive ability is a fact that cannot be ignored. Especially in the elderly, the decline in executive ability and the decline in learning and memory is veryRead more

SARS-CoV-2 is an enveloped single-stranded RNA virus. The viral RNA produces two polyproteins: pp1a and pp1ab through ribosome frameshift. The polyprotein is processed by the papain-like protease (PL pro), which cuts 3 sites to release the non-structural protein nsp1-3 and a 3C-like protease, also known as the main protease (M pro). Cut at 11 sitesRead more

Shanghai Medicilon has extensive and extensive experience in molecular biology services, in vitro biology, cell biology services and structural biology. From the initial cDNA library construction to drug design, through protein purification, structure determination and analytical determination, we provide a complete set of biological technical services. Currently opened projects include recombinant proteins, protein expression (yeast,Read more

Medicilon’s chemical department has comprehensive chemical research capabilities and facilities including medicinal chemistry, synthetic chemistry, process research and analytical support, and professional synthetic technology. It has a good record of project advancement and the generation of preclinical drug candidates. We can quickly complete new drug development projects from compound screening to new drug clinical researchRead more

Metabonomics (metabonomics) refers to the analysis of group indicators, high-throughput detection and data processing, and the dynamic metabolic changes of the overall body or tissue cell system of graduate students, especially for endogenous metabolism, genetic variation, environmental changes and even various. The subject of the characteristics and effects of substances entering the metabolic system. MetabolomicsRead more

Pharmaceutical R&D Outsourcing Service Project Medicilon is known as one of the drug R&D outsourcing service companies (CRO). It has established a company in Shanghai that integrates compound synthesis, compound activity screening, structural biology, pharmacodynamic evaluation, pharmacokinetic evaluation and toxicology evaluation. The comprehensive technical service platform in line with international standards has been recognized byRead more

The advantages of Medicilon protein expression service are short experiment period, low cost and high yield. Protein expression refers to a molecular biology technique that uses model organisms such as bacteria, yeast, animal cells or plant cells to express foreign gene proteins. It occupies a core position in genetic engineering technology. Recombinant protein expression andRead more

Medicilon’s proteomics technology service integrates multiple technologies such as biochemistry, cell biology, molecular biology, and mass spectrometry to enable protein identification, differential protein quantitative analysis, complex separation, and protein post-translational modification (eg, phosphorylation) , Glycosylation, ubiquitination, etc.) analysis and proteomics informatics analysis. Proteomics essentially refers to studying the characteristics of proteins at a large scale,Read more

The Bio-Plex suspension chip multiple detection platform can simultaneously detect up to 100 molecules in the same sample. Because of its good reproducibility in data, it is now widely used in immunology and various disease research. Such as cardiovascular disease, biomarker screening of tumor-specific markers, development of drug therapy targets, evaluation of drug treatment effects,Read more

The biological department of Shanghai Medicilon has extensive experience in the field of in vitro biology, through enzyme level measurement, cell level measurement, cell biology, biochemistry, in vitro isotope measurement, stable cell line establishment, gene knockout, RNAi and MicroRNA Technology, etc., to provide a complete set of biological services. Medicilon Enzyme Level Determination Service EnzymeRead more

The main instruments used in molecular biology services include gel imaging systems, autoclaves and other instruments. The Medicilon molecular biology department has professional technical staff and advanced equipment, which is the most suitable for molecular outsourcing experiments. 1. Gel imaging system Technical Parameters: 1. Professional high-definition black and white CCD, patented CCD horizontal technology. EffectiveRead more

The biological department of Shanghai Medicilon has extensive experience in the fields of molecular biology, cell biology, in vitro biology and structural biology. From the initial cDNA library construction to drug design, through protein purification, structure determination and analytical determination, we provide a complete set of biological services. Main content of cell experiment technical serviceRead more