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Jan 04,2022
With its strength on the list, Medicilon was successfully identified as the "Shanghai Enterprise Technology Center"
On December 9th, the publicity of the list of recognized municipal enterprise technology centers in Shanghai for 2021 (the 27th batch) was completed. Medicilon was recognized as the "Shanghai Enterprise Technology Center" with its solid R&D capabilities and technological innovation capabilities.
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Nov 29,2021
Biacore Analysis of Medicilon
As a high-throughput test system, Biacore 8K can help customers analyze a large number of samples in a short period of time. Biacore™ 8K can complete the screening, affinity and kinetic characterization of small molecule compound drugs and biotherapeutics at the speed you dream of, and provide the high-quality data you expect. As a newRead more
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Dec 09,2021
Medicilon’s Preclinical Bioanalysis
Biotechnology drugs are known as one of the most promising fields in drug research and development in the 21st century. In recent years, more and more drug development has focused on this, and its bioanalysis has therefore attracted more and more attention. Medicilon’s preclinical bioanalysis service team is composed of nearly 20 experienced technical personnel,Read more
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Nov 24,2021
ELISA Protocol-Elisa Experiment Standard Operating Method
The Elisa experiment has been widely used clinically due to its high sensitivity and good specificity. However, each link in the operation has a greater impact on the detection effect of the experiment. If you are not careful, it may lead to incomplete color rendering and patterning. Wait for the result. ELISA Protocol The followingRead more
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Nov 03,2021
Influence of Hemolysis on the Analysis of Biological Samples
Hemolysis refers to the rupture of red blood cells and the escape of hemoglobin into plasma or serum, which can occur in vivo and in vitro. The factors affecting hemolysis are also very complicated. After hemolysis of plasma and serum, many physiological components such as hemoglobin, bilirubin, phospholipids, etc. increase significantly. These components may affectRead more
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Oct 21,2021
Development and Verification of Analysis Methods for Disposable Systems
The dissolution/precipitate evaluation is an important part of the process-specific verification of filters and disposable systems in the pharmaceutical field to examine the applicability of equipment (including filters and disposable systems) in specific processes. This article describes the development and validation of the dissolution/precipitate analysis method for the verification test of the dissolution/precipitate, and introducesRead more
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Oct 21,2021
HPLC Analysis Method Development and Verification System
Analytical method development The development of analytical methods mainly includes the selection of chromatographic columns, the selection of mobile phases, the selection of detection wavelengths, and the optimization of gradients. At present, HPLC is mostly used in reversed phase, so this article mainly uses reversed phase as an example to explain. Selection of Column TheRead more
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Oct 13,2021
Analysis of the Difference Between Intermediates and APIs
Intermediates refer to intermediate products in the process of compound synthesis. Pharmaceutical intermediates are some chemical APIs or chemical products used in the synthesis process of APIs. They do not require a production license for APIs and can be produced in ordinary chemical plants. , As long as it reaches a certain level, it canRead more
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Oct 12,2021
Types and Analysis of Residual Solvents in the R&D and Production of APIs
Residual solvents in drugs are defined in Q3C as organic volatile compounds produced or used in the production of bulk drugs or excipients, and during the preparation of the formulations, and they cannot be completely eliminated in the process. In the process of drug substance impurity analysis, the study of residual solvents has attracted muchRead more
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Sep 18,2021
Preclinical Research Company
Medicilon is a company engaged in pre-clinical research services (CRO), which specializes in providing customers with customizable pre-clinical trial service programs. Professional knowledge in pharmacodynamic research and toxicology. Provide you with high-quality data and fast turnaround to support various drug development, preclinical research and clinical research. Help you select the most valuable drug candidates intoRead more
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Sep 17,2021
Medicilon Cytotoxicity Test Service
The Biology Department of Shanghai Medicilon has extensive experience in the field of in vitro biology, through enzyme level determination, cell level determination, cell biology, biochemistry, in vitro isotope determination, stable cell line establishment, gene knockout, RNAi and MicroRNA Technology, etc., to provide a complete set of biological services. Cytotoxicity test Medicilon Cell Level MeasurementRead more
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Sep 13,2021
Study on the Pharmacokinetics of Gastrodin and its Pharmacological Effects
Gastrodia is a dry tuber of the orchid plant Gastrodia elata. It is a traditional and precious Chinese medicine for calming the liver, relieving wind and relieving spasm. Gastrodin is the main active ingredient of Gastrodia. Pharmacological studies have shown that Gastrodia has sedative, anti-convulsant, anti-epileptic properties, and increases cerebral blood flow. Protect nerve cellsRead more
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Sep 13,2021
Medicilon appoints Dr. Hong Wan as Vice President of DMPK and Bioanalysis Department
Recently, Shanghai Medicilon Inc. (stock code: 688202.SH) (Medicilon) announced the appointment of Dr. Hong Wan as Vice President of DMPK and Bioanalysis Department. Dr. Hong
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Sep 10,2021
The Consistency Evaluation of Generic Drugs Requires Attention to the Particle Size of API
In the development of pharmaceutical preparations, due to the different synthesis processes of API from different sources, there may be differences in their solubility, crystal form, particle size, and impurities, which may affect the consistency of the product. In the evaluation of the consistency of generic drugs, the particle size control of API should notRead more
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Sep 07,2021
Analysis of the role of GLP regulations and ideas
The pharmaceutical production quality assurance system-Pharmaceutical Non-clinical Research Quality Management Practices (GLP) is the key to improving the quality of pharmaceuticals. It is a common practice for non-clinical drug safety evaluation work in the world, and it is also the international toxicology data exchange and mutual recognition of information. The basics. The GLP laboratories ownedRead more
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Sep 06,2021
Analysis of the Characteristics of Aerosol and Preformulation Research
Aerosol is a dosage form of medicine. It is a dispersion system composed of fine liquid droplets or solid particles (dispersed inner phase) in air or mixed gas (dispersed outer phase). The dispersed ions are extremely small, and the diameter is from 1 to hundreds of nanometers. , Generally divided into high, medium and lowRead more
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Sep 03,2021
Things you have to know about the Western Blot Experiment
Western Blot, also known as western blot analysis and immunoblotting, is a technique widely used in the detection and analysis of proteins. It uses polyacrylamide gel electrophoresis. “Use a labeled secondary antibody. Western blot analysis is a commonly used experimental method in molecular biology, biochemistry and immunogenetics. Medicilon Biopharmaceuticals can provide Western blotting experimental technologyRead more
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Sep 03,2021
Application of Western Blot Analysis in Studying the Proliferation of NM23B Gene Cells
NM23 is a tumor metastasis suppressor gene, which has regulatory functions on cell proliferation, differentiation and ontogeny. At present, 10 subtypes of NM23 have been found, and the more thorough research is NM23A and NM23B. Western blot analysis shows that NM23B has hepatocyte proliferation effect on SD rats cultured in vitro. Western blot analysis, alsoRead more
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Sep 03,2021
Western blot analysis technique in detecting protein expression level
Lung cancer is one of the most harmful malignant tumors. To explore the pathogenesis of lung cancer and find new targets for anti-tumor therapy are the hotspots and difficulties in the current research on lung cancer treatment. Studies have found that aquaporin 4 (AQP4) is highly expressed in lung cancer cells, and knocking down AQP4Read more
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Aug 30,2021
Analysis on the Method of Yeast Two-hybrid Library Construction
Yeast two-hybrid technology is an important experimental method in the field of molecular biology research. It uses yeast genetics to analyze the interactions between proteins. It has now been widely used in proteomics, cell signal transduction, and functional genomics. . Yeast two-hybrid library construction generally includes two methods: nuclear system and membrane system. The nuclearRead more
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