ABOUT
Inhalation Drug Delivery
- Medicilon is familiar with the development process of various inhalation preparations, especially in the fields of Dry Powder Inhaler (DPI), Nebulizer and Nasal Spray preparations. During the research process, all work is fully compliant with the requirements of regulatory agencies and guiding principles. Medicilon is equipped with equipment such as COPLEY's Next Generation Impactor (NGI), COPLEY's BRS 2100 Breath Simulator, Particle Size Analyzer from Sympatec and other equipment, which meets the requirements of in vitro inhalation assessment. So far, Medicilon has supported a number of companies that carry out research on inhalation preparations, and has completed a number of quality research work on protein inhalation preparations, inhalation solutions and nebulizers.
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Our services
Nebulizer
Nasal Spray
Research and development of Dry Powder Inhaler (DPI)
Quality study of various inhalation preparationsMedicilon cases studies
Acetylcysteine Solution for Inhalation, Mometasone Furoate Aqueous Nasal Spray, etc.
Device configuration
Ophthalmic Drug Delivery
- Due to an aging population, widespread use of electronic products, and changes in living habits, the incidence of eye diseases such as Eye Infection, Conjunctivitis, Macular Degeneration, and Dry Eye Syndrome has increased significantly. Medicilon has accumulated significant project experience in solution, suspension and semi-solid ophthalmic preparations, and is familiar with various packaging forms and BFS technologies.
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Our services
Ophthalmic liquid preparations (solutions, suspensions)
Research and development of ophthalmic semi-solid preparations (eye ointment, gel, etc.)
Medicilon cases
Moxifloxacin Hydrochloride Ophthalmic Solution, Atropine Sulfate Eye Drops, New drug suspension eye drops.
Transdermal Drug Delivery
- Transdermal Therapeutic System (TTS) or Transdermal Delivery System (TDS) refers to a dosage form in which a drug enters the circulatory system through the skin surface at a constant rate (or near-constant rate) to produce systemic or local therapeutic effects. Transdermal dosage forms are patches, ointments, plasters, liniments and aerosols.In vitro Release Test (IVRT) and In vitro Penetration Test (IVPT)are important means to evaluate the dosage forms and prescriptions of external preparations. Medicilon has rich experience in evaluation of transdermal drug delivery preparations and is equipped with corresponding transdermal and detection instruments (LC-MS/MS), which can be used in compound screening, new drug application, pharmaceutical changes and consistency of listed chemicals. We provide professional and efficient service for projects involving in vitro evaluation.
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Our services
Research and development of TTS/TDS including creams, ointments, gels and liniments.
We can deliver in vitro release testing and in vitro penetration testing.
Medicilon cases
Tacrolimus Ointment, Minoxidil Tincture, Clindamycin Phosphate and Benzoyl Peroxide Gel, Progesterone Sustained-release vaginal gel, Metronidazole Vaginal Gel, Triamcinolone Acetonide Acetate Ointment, Neticonazole Hydrochloride.
Device configuration
Sustained-and Controlled-Release Drug Delivery
- Medicilon has a variety of sustained and controlled release drug delivery technologies, such as water dispersion coated sustained-release pellets, Laser drilling osmotic pump controlled-release, and matrix-type sustained-release technologies. Our sustained-and controlled-release preparation technology platform is dedicated to the development and scale-up research of sustained-and controlled-release preparations, improving on matrix-type and reservoir-type sustained- and controlled-release drug delivery systems, established and improved the in vitro test methods and related standards of various oral sustained- and controlled-release preparations.
Our services
Development and scale-up of matrix-type and depot-type sustained and controlled release preparations
Quality evaluation of matrix-type and depot-type sustained and controlled release preparations
Medicilon has delivered,
Oxycodone Hydrochloride Prolonged-release Tablets, Quetiapine Fumarate Extended-Release Tablets, Paroxetine Hydrochloride Enteric-Coated Sustained-Release Tablets.
Microparticle Drug Delivery
- Microparticle Drug Delivery Systems (MDDS) can increase the solubility of insoluble drugs, improve the stability of drug particles and can achieve sustained release and targeting. MDDS has the advantages of high drug loading, high bioavailability, less local and systemic side effects, less fluctuation of blood drug concentration, and high efficacy and patient compliance. In recent years, drug development has focused on formulations such as microemulsions, liposomes, nanoparticles, and microspheres.
Our services
Pre-prescribing of Microparticle Drug Delivery
Formulation process research
Analytical method development.