Bioanalytical Services

Medicilon offers a full range of Bioanalytical Services supporting various aspects of the drug discovery and development continuum, including discovery biology, in vitro ADME, preclinical PK/PD, GLP-compliant toxicology, as well as bioequivalence studies and clinical trials.
Led by Dr. Baomin Xin, a well-established expert from Bristol-Myers Squibb, our experienced team is dedicated to bioanalytical sciences and has up-to-date knowledge of compliance requirements. We utilize the latest platforms and technologies from Sciex, Waters, Shimadzu, Hamilton Star, Gyros, BioPlex, MSD, and Thermo Watson, to generate high-quality data and help you to turn your molecules to medicines quickly and cost-effectively.

LC-MS/MS Systems

• Sciex Triple Quad 6500+
• Sciex Triple Quad 5500
• Shimadzu LCMS-8050
• Sciex API 4000
• Waters Acquity UHPLC
• Shimadzu Nexera UHPLC

LBA Instruments

• GE Biacore 8K SPR System
• Gyrolab xPlore
• Meso Scale Discovery SECTOR Imager S600
• Bio-Plex 200 Multiplex Immunoassay System
• Molecular Devices SpectraMax i3x, M4, and M5 Plate Readers
• Hamilton Automated Liquid Handling Workstation
• Applied Biosystems 7500 Real Time PCR System
• BioTek ELx405 Select Microplate Washer

Biological Sample Storage & Preparation Equipments

• Biotage Lycera Bead Mill Homogenizer
• MP Bio Fastprep-24 Bead Mill Homogenizer
• IKA ULTRA-TURRAX T25 Digital Disperser
• Agela SPE-M96 Positive Pressure Device
• Biotage SPE Dry 96 Sample Concentrator
• Milli-Q Academic
• Eppendorf Refrigerated Centrifuges

1. LC-MS/MS method development
2. LC-MS/MS method transferL/li>
3. LC-MS/MS method validation
   • Full validation
   • Partial validation
   • Cross validation
4. Blood plasma sample analysis
5. Tissue sample analysis

Applicable to a wide range of biomatrix. Preclinical and clinical sample analysis