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Syngeneic Mouse Models

Syngeneic Mouse Models

Syngeneic mouse models test the ability of animals to fight cancer with an intact immune system and is used to test the therapeutic effects of immunotherapy. We can provide various syngeneic models to test the effectiveness of drugs according to our clients' requirements. Typical orthotopic disease models include breast cancer, lung cancer, colon cancer, kidney cancer and diffuse large B-cell lymphoma (DLBCL), utilising mice, rats and hamsters as test subjects.
Medicilon icon-diamond.pngModel Type
                     Cancer Type                    Cell Lines
AMLC1498,L1210, WEHI-3
Bladder cancerMB49
Breast cancerEMT6, JC,EO771(ATCC), 4T1,4T1-luc,  C1271
Colon cancerCT26.WT, CT26.WT-luc, MC-38,  Colon26, CMT-93
DLBCL lymphomaA20,P388D1, L5178-R (LY-R),E.G7-OVA
Kidney cancerRENCA
LeukemiaC1498, L1210, WEHI-3
Liver cancerH22, H22-Luc, Hepa 1-6
Lung cancerLLC1, LLC1-luc, KLN205
LymphomaA20, EL4, L5178-R, E.G7-OVA
MelanomaB16-F10, Clone-M3
Renal cancerRENCA
Pancreatic cancerPanc 02
  • Classification of immune cells in model blood by flow cytometry (FCM).png
  • Detection of efficacy of PD-1 drugs by syngeneic mouse models.png
Relevant laboratories
  • flow cytometer
  • caliper
  • FCM
  • Frozen section
  • FCM
  • IVIS-Lumina-III-In-Vivo-Imaging-System
  • pathological section
  • animal breeding room
Relevant articles