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Top 10 Global Clinical Research Organizations in 2021| Top 10 Global CDMO Enterprises| Preclinical Drug Development Process
Mar 03,2023
Whole-Process of Antibody Drug Development - Facilitate IND Declaration of Biological Drugs
The Medicilon antibody development platform has been deeply involved in the field of antibody drug research and development and their technical services include the ADA antibody development technical services and druggable antibody development technical services, ADA-free polyclonal antibody development, ADA mouse hybridoma monoclonal antibody development, phage display rabbit monoclonal antibody development services, mouse monoclonal antibody development technical services, mouse/rabbit single B cell antibody development technical services and other projects.
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Whole-Process of Antibody Drug Development - Facilitate IND Declaration of Biological Drugs
Feb 24,2023
Beautiful Chemistry-Photoinduced Alkene Cleavage Using Nitroarenes
The oxidative cleavage of olefins is an important transformation in organic synthesis to obtain carbonyl functional groups such as ketones and aldehydes. Medicilon has integrated emerging methods of green chemistry into its services, using currently popular photoredox chemistry, electrochemisty, catalyst screening, continuous reactions, etc., to provide our customers with high-quality economic solutions.
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Beautiful Chemistry-Photoinduced Alkene Cleavage Using Nitroarenes
Feb 17,2023
Come, Chat with ChatGPT regarding CRO
Almost overnight, the whole city chatted about ChatGPT. While people are admiring the omnipotence of AI, people also worry that their jobs will be taken away by AI one day...
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Come, Chat with ChatGPT regarding CRO
Feb 17,2023
Market Prospects, Development Challenges and Countermeasures of Oligonucleotide Drugs
In recent years, with the advancement of related research and technology, nucleic acid drugs have ushered into rapid development, and the number of nucleic acid drugs approved for the global market is increasing yearly.
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Market Prospects, Development Challenges and Countermeasures of Oligonucleotide Drugs
Feb 04,2023
World Cancer Day: Features of Popular Tumor Models in Oncology Drug Development
February 4th is the 24th World Cancer Day. Medicilon has been part of the great human effort to combat cancer since its founding in 2004. In order to better understand tumorigenesis, to foster cancer prevention and to develop novel anti- cancer therapy, Medicilon has been providing IND enabling preclinicalservice for 19 years, and has established close to 300 tumor evaluation model for R&D.
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World Cancer Day: Features of Popular Tumor Models in Oncology Drug Development
Jan 05,2023
The Role of the Ames Test in Predicting the Genotoxicity of Impurity Compounds in Drugs
The Ames test is short-term in vitro test method for preliminary screening of the mutagenicity of chemical substances by using the properties of the reverse mutation of the histidine auxotrophic mutant strain of Salmonella typhimurium.
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The Role of the Ames Test in Predicting the Genotoxicity of Impurity Compounds in Drugs
Jan 02,2023
​Aim at chemical synthesis through Ibuprofen
The synthesis of Ibuprofen starts from isobutyl benzene. The synthesis procedure includes Friedel-Crafts acylation, reduction, chloride substitution, and Grignard reaction. The products of each step were then analyzed by IR and 1 H NMR spectroscopy, and the final product was confirmed by analysis of melting points.
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​Aim at chemical synthesis through Ibuprofen
Dec 27,2022
What is Meant by Target Validation and How is Target Validation Done?
Target validation refers to the accumulation of scientific evidence that a target (usually a protein) is modulated (usually inhibited) for therapeutic use.
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What is Meant by Target Validation and How is Target Validation Done?
Dec 26,2022
"China's Pharmaceutical CDMO Industry Map in 2021" is Coming-Echelon Ranking and Distribution
As an essential part of the new drug research and development industry, the company provides services throughout the entire life cycle of the drug, from preclinical research to clinical phase I and before the drug patent expires.
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"China's Pharmaceutical CDMO Industry Map in 2021" is Coming-Echelon Ranking and Distribution
Dec 26,2022
CDMO Development Enters the Fast Lane
The primary source of CDMO demand is the outsourcing part of process development and experimental drug production of large and small pharmaceutical companies.
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CDMO Development Enters the Fast Lane